Vilazodone-d8

Vilazodone-d8 Structure
CAS No.
1794789-93-7
Chemical Name:
Vilazodone-d8
Synonyms
Vilazodone-d8;EMD 515259-d8;5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-(piperazinyl-d8)]-2-benzofurancarboxaMide;Vilazodone D8Q: What is Vilazodone D8 Q: What is the CAS Number of Vilazodone D8 Q: What is the storage condition of Vilazodone D8 Q: What are the applications of Vilazodone D8
CBNumber:
CB82545851
Molecular Formula:
C26H26N5O2
Molecular Weight:
440.51694
MOL File:
1794789-93-7.mol
Modify Date:
2024/7/2 8:55:20

Vilazodone-d8 Properties

Melting point 195-198°C
storage temp. Refrigerator
solubility Water: 0.32 mg/ml
form A solid
color White to off-white

Vilazodone-d8 Chemical Properties,Uses,Production

Description

Vilazodone-d8 is intended for use as an internal standard for the quantification of vilazodone by GC- or LC-MS. Vilazodone is a selective serotonin reuptake inhibitor (SSRI) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A (IC50s = 0.2 and 0.5 nM, respectively). It increases extracellular 5-HT in the rat ventral hippocampus and frontal cortex when administered intraperitoneally at doses of 1 and 3 mg/kg, respectively. Vilazodone (1 mg/kg, i.p.) decreases immobility in the forced swim test in both rats and mice. Formulations containing vilazodone have been used in the treatment of depression.

Chemical Properties

Off-White to Pale Yellow Solid

Uses

(Vilazodone-d8) Labelled Vilazodone. It is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression. Antidepressant.;Labeled Vilazodone, intended for use as an in

Vilazodone-d8 Preparation Products And Raw materials

Raw materials

Preparation Products

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5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-(piperazinyl-d8)]-2-benzofurancarboxaMide EMD 515259-d8 Vilazodone-d8 Vilazodone D8Q: What is Vilazodone D8 Q: What is the CAS Number of Vilazodone D8 Q: What is the storage condition of Vilazodone D8 Q: What are the applications of Vilazodone D8 1794789-93-7 C26H19D8N5O2 Amines Aromatics Heterocycles Intermediates & Fine Chemicals Isotope Labelled Compounds Pharmaceuticals