Ethylene glycol diphenyl ether
- CAS No.
- 104-66-5
- Chemical Name:
- Ethylene glycol diphenyl ether
- Synonyms
- 1,2-DIPHENOXYETHANE;DIPHENYL GLYCOL;1,2-Diphenoxyethan;sym-Diphenoxyethane;DIPHENYL CELLOSOLVE;Domiphen Impurity 5;Diphenoxyethane (DPE);Ethane,1,2-diphenoxy-;Ethlene diphenyl ether;Ethane, 1,2-diphenoxy-
- CBNumber:
- CB8260956
- Molecular Formula:
- C14H14O2
- Molecular Weight:
- 214.26
- MOL File:
- 104-66-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/29 16:45:47
| Melting point | 94-96 °C (lit.) |
|---|---|
| Boiling point | 185 °C / 12mmHg |
| Density | 1.0781 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5570 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 22mg/L at 25℃ |
| BRN | 2052248 |
| InChIKey | XCSGHNKDXGYELG-UHFFFAOYSA-N |
| LogP | 3.81 at 25℃ |
| CAS DataBase Reference | 104-66-5(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Phenoxyethyl phenyl ether (104-66-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H411 | |||||||||
| Precautionary statements | P273-P391-P501 | |||||||||
| Risk Statements | 51/53 | |||||||||
| Safety Statements | 22-24/25-61-36-29/56 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29093090 | |||||||||
| NFPA 704 |
|
Ethylene glycol diphenyl ether price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 140287 | 1,2-Diphenoxyethane 99% | 104-66-5 | 5G | ₹1558.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 140287 | 1,2-Diphenoxyethane 99% | 104-66-5 | 5G | ₹1558.8 | 2022-06-14 | Buy |
| TCI Chemicals (India) | D0866 | Ethylene Glycol Diphenyl Ether min. 99.0 % | 104-66-5 | 5G | ₹3400 | 2022-05-26 | Buy |
Ethylene glycol diphenyl ether Chemical Properties,Uses,Production
Chemical Properties
Off-white Crystals
Uses
1,2-Diphenoxyethane is a reagent that is used in the production and use of activatable delivery compounds containing drugs or a detectable moiety and singlet oxygen-labile linkers.
Preparation
The preparation of Ethylene glycol diphenyl ether is as follows:A three-necked flask was charged with 15.7 g of bromobenzene (100 mmol) and 47 ml of DMF, and stirred. 12.7 g of sodium carbonate (120 mmol, 1.2 eq.), 1.9 g of cuprous iodide (10 mmol, 0.1 eq.), 1.87 g of 2,2'-bipyridine (12 mmol, 0.1 eq.) and 7.4 g of ethylene glycol (120 mmol, 1.2 equivalent), the reaction mixture was stirred at 100 ° C overnight. After recovering DMF under reduced pressure, 100 ml of water and 100 ml of toluene were added, and the aqueous phase was extracted three times with 300 ml of toluene, and the organic layers were combined. Washed sequentially with 5% sodium carbonate. The organic phase was dried over anhydrous sodium sulfate, filtered, and then filtered and evaporated,The crude product was recrystallized from isopropanol and dried in vacuo to give 19.5 g of product, yield 91%, purity over 99%.
Application
Ethylene glycol diphenyl ether can be used as a new heat-sensitive material sensitizer and a potential polyolefin catalyst additive.
General Description
1,2-Diphenoxyethane is the intermediate formed during sonochemical oxidation of phenoxyacetic acid and chlorophenol.
Ethylene glycol diphenyl ether Preparation Products And Raw materials
Raw materials
1of2
chevron_rightPreparation Products
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|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
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| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21665 | 55 | Inquiry |
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| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 18628 | 58 | Inquiry |
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 | China | 299 | 55 | Inquiry |