H-Aib-OBzl
![H-Aib-OBzl Structure](CAS/20150408/GIF/60421-20-7.gif)
- CAS No.
- 60421-20-7
- Chemical Name:
- H-Aib-OBzl
- Synonyms
- aib-obzl.hcl;H-Aib-Obn.HCl;H-Aib-OBzl USP/EP/BP;Benzyl 2-amino-2-methylpropanoate HCl;Benzyl α-aminoisobutyrate hydrochloride;Benzyl α-aminoisobutyrate hydrochloride;2-Methylalanine benzyl ester hydrochloride;Benzyl alpha-aMinoisobutyrate hydrochloride;Benzyl 2-amino-2-methylpropionate hydrochloride;2-Aminoisobutyric acid benzyl ester hydrochloride
- CBNumber:
- CB82620071
- Molecular Formula:
- C11H16ClNO2
- Molecular Weight:
- 229.70324
- MOL File:
- 60421-20-7.mol
- Modify Date:
- 2023/10/25 10:27:13
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H317-H319 |
Precautionary statements | P280-P305+P351+P338 |
WGK Germany | 3 |
H-Aib-OBzl Chemical Properties,Uses,Production
Chemical Properties
Benzyl 2-amino-2-methylpropanoate hydrochloride, also known as H-Aib-OBzl, is a white solid.
Preparation
A mixture of 2-amino-2- methylpropanoic acid (3 g, 29.1 mmol), benzyl alcohol (12 mL, 115 mmol), and p- toluenesulfonic acid monohydrate (5.53 g, 29.1 mmol) in toluene (40 mL) was heated under reflux overnight. Additional benzyl alcohol (12 mL, 115 mmol) was added and the reaction mixture was heated with a Dean Starck overnight. The reaction mixture was concentrated under reduced pressure and washed with diethyl ether. Diethyl ether was removed, and then the residue was dissolved in ethyl acetate and washed with a saturated aqueous NaHC03 solution. The organic layer was dried over Na2S04 and concentrated under reduced pressure. The resulting product was triturated with diethyl ether and HCI in dioxane. The solid was filtered, washed with diethyl ether and dried under reduced pressure to afford benzyl 2-amino-2-methylpropanoate hydrochloride (H-Aib-OBzl).
Waste Disposal
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
H-Aib-OBzl Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 | China | 1106 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24330 | 58 | Inquiry |
BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | China | 19915 | 58 | Inquiry |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20296 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
DONBOO AMINO ACID COMPANY | +8613063595538 | China | 9365 | 58 | Inquiry |