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Seratrodast

CAS No.: 112665-43-7

Chemical Name:: Seratrodast

Synonyms: Bronic;CS-324;aa-2414;Bronica;Seretra;ABT-001;Serabenast;CCRIS 8939;Seratrodast;50MG/200MG/1G

CBNumber:: CB8284400

Molecular Formula:: C22H26O4

Molecular Weight:: 354.44

MOL File:: 112665-43-7.mol

MSDS File:: SDS

Modify Date:: 2024/11/19 20:33:22

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Seratrodast Properties

Melting point	118-120°C
Boiling point	522.3±49.0 °C(Predicted)
Density	1.140±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	4.76±0.10(Predicted)
form	Yellow-orange solid.
color	Pale Orange to Yellow
Merck	14,8459
CAS DataBase Reference	112665-43-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Warning
Hazard statements	H361
Precautionary statements	P201-P202-P280-P308+P313-P405-P501
RTECS	DA1600050
HS Code	2918.30.3000

Seratrodast price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemicals (India)	S0943	Seratrodast	112665-43-7	100MG	₹5700	2022-05-26	Buy
TCI Chemicals (India)	S0943	Seratrodast	112665-43-7	1G	₹9800	2022-05-26	Buy

Product number	Packaging	Price	Buy
S0943	100MG	₹5700	Buy
S0943	1G	₹9800	Buy

Seratrodast Chemical Properties,Uses,Production

Description

Seratrodast, a novel benzoquinone derivative, is the first thromboxane A₂ (TxA₂) receptor antagonist to reach the market. It is orally active for the treatment of bronchospastic disorders such as asthma. TxA₂, a metabolite of the arachidonate cascade, is involved in several cardiovascular and respiratory diseases through its potent biological effects on platelet aggregation and constriction of vascular and respiratory smooth muscles. Seratrodast potently inhibits platelet aggregation and bronchoconstriction induced by a TxA₂ mimic and by a variety of spasmogenic prostanoids including PGF_2α, PGD₂ and 9α,11β-PGF₂. Seratrodast shows excellent efficacy in asthma and has been reported to be potentially useful in hyper-responsive disorder. The R-(+)- seratrodast was reported to be the active isomer.

Chemical Properties

Pale Orange Solid

Biological Activity

Thromboxane A 2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA 2 mimetic in guinea pigs.

Seratrodast Preparation Products And Raw materials

Raw materials

(1S)-(+)-Camphor-10-sulphonic acid Trimethylhydroquinone Phenol Ferric chloride Heptanoic acid

Preparation Products

Seratrodast Suppliers

Global( 238)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Manus Aktteva	+91 (79) 6512-3395	New Delhi, India	581	34	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6700	30	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6768	58	Inquiry
MANGALAM DRUGS AND ORGANICS LIMITED	08147509329	Uttar Pradesh, India	50	58	Inquiry
Indogulf Group	91-22-23455220	Maharashtra, India	249	58	Inquiry
ARCHERCHEM	91-22-28786843/ 91-22-28786842 /91-22-28786842	New Delhi, India	86	54	Inquiry
Athos Chemicals	91-9998858909	Gujarat, India	315	58	Inquiry
Manus Aktteva Biopharma LLP	08048250218Ext 800	Ahmedabad, India	655	58	Inquiry
Shivam Pharma Chemicals	91-22-26403900	Maharashtra, India	656	58	Inquiry

Supplier	Advantage
Manus Aktteva	34
CLEARSYNTH LABS LTD.	58
CHEMSWORTH	30
TCI Chemicals (India) Pvt. Ltd.	58
MANGALAM DRUGS AND ORGANICS LIMITED	58
Indogulf Group	58
ARCHERCHEM	54
Athos Chemicals	58
Manus Aktteva Biopharma LLP	58
Shivam Pharma Chemicals	58

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7-PHENYLHEPTANOIC ACID 1,4-HEXADIENE Heptanoic acid

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50MG/200MG/1G benzeneheptanoic acid, -(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)- (+-)-7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoicacid aa-2414 beta-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-bezeneheptanoicaci 5-(2,4,5-trimethyl-3,6,-dioxo-1,4-cyclohexadien-1-yl)benzeneheptanoic acid 7-(3,5,6-trimethy1-1,4-benzoquinon-2-y1)-7-phenylheptanoic acid 7-phenyl-7-(2,4,5-trimethyl-3,6-dioxo-1-cyclohexa-1,4-dienyl)heptanoic acid Bronica Abbott 73001 Bronic (±)-ζ-2，4，5-Trimethyl-3，6-dioxo-1，4-cyclohexadien-1-y1)benzeneheptanoic acid 7-(3,6-diketo-2,4,5-trimethyl-cyclohexa-1,4-dien-1-yl)-7-phenyl-enanthic acid 7-phenyl-7-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,4-dien-1-yl)heptanoic acid 7-phenyl-7-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)heptanoic acid Serabenast Seratrodast Seratrodast(AA-2414,ABT-001) AA-2414;SERETRA;AA2414;AA 2414 Seretra Seratrodast AA 2414 CS-324 Seratrodast > ABT-001 Seratrodast USP/EP/BP CCRIS 8939 112665-43-7 C22H26O4 ZAGAM API Heterocyclic Compounds Intermediates & Fine Chemicals Pharmaceuticals