Seratrodast
![Seratrodast Structure](CAS/GIF/112665-43-7.gif)
- CAS No.
- 112665-43-7
- Chemical Name:
- Seratrodast
- Synonyms
- Bronic;CS-324;aa-2414;Bronica;Seretra;ABT-001;Serabenast;CCRIS 8939;Seratrodast;50MG/200MG/1G
- CBNumber:
- CB8284400
- Molecular Formula:
- C22H26O4
- Molecular Weight:
- 354.44
- MOL File:
- 112665-43-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/11/14 14:35:52
Melting point | 118-120°C |
---|---|
Boiling point | 522.3±49.0 °C(Predicted) |
Density | 1.140±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
pka | 4.76±0.10(Predicted) |
form | Yellow-orange solid. |
color | Pale Orange to Yellow |
Merck | 14,8459 |
CAS DataBase Reference | 112665-43-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
---|---|
Signal word | Warning |
Hazard statements | H361 |
Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
RTECS | DA1600050 |
HS Code | 2918.30.3000 |
Seratrodast price More Price(2)
Seratrodast Chemical Properties,Uses,Production
Description
Seratrodast, a novel benzoquinone derivative, is the first thromboxane A2 (TxA2) receptor antagonist to reach the market. It is orally active for the treatment of bronchospastic disorders such as asthma. TxA2, a metabolite of the arachidonate cascade, is involved in several cardiovascular and respiratory diseases through its potent biological effects on platelet aggregation and constriction of vascular and respiratory smooth muscles. Seratrodast potently inhibits platelet aggregation and bronchoconstriction induced by a TxA2 mimic and by a variety of spasmogenic prostanoids including PGF2α, PGD2 and 9α,11β-PGF2. Seratrodast shows excellent efficacy in asthma and has been reported to be potentially useful in hyper-responsive disorder. The R-(+)- seratrodast was reported to be the active isomer.
Chemical Properties
Pale Orange Solid
Biological Activity
Thromboxane A 2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA 2 mimetic in guinea pigs.
Seratrodast Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Manus Aktteva | +91 (79) 6512-3395 | New Delhi, India | 581 | 34 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
MANGALAM DRUGS AND ORGANICS LIMITED | 08147509329 | Uttar Pradesh, India | 50 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
Indogulf Group | 91-22-23455220 | Maharashtra, India | 249 | 58 | Inquiry |
Athos Chemicals | 91-9998858909 | Gujarat, India | 315 | 58 | Inquiry |
ARCHERCHEM | 91-22-28786843/ 91-22-28786842 /91-22-28786842 | New Delhi, India | 86 | 54 | Inquiry |
Shivam Pharma Chemicals | 91-22-26403900 | Maharashtra, India | 656 | 58 | Inquiry |
Manus Aktteva Biopharma LLP | 08048250218Ext 800 | Ahmedabad, India | 655 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Manus Aktteva | 34 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
MANGALAM DRUGS AND ORGANICS LIMITED | 58 |
CLEARSYNTH LABS LTD. | 58 |
CHEMSWORTH | 30 |
Indogulf Group | 58 |
Athos Chemicals | 58 |
ARCHERCHEM | 54 |
Shivam Pharma Chemicals | 58 |
Manus Aktteva Biopharma LLP | 58 |