Propargyl-PEG4-acid

Propargyl-PEG4-acid Structure
CAS No.
1415800-32-6
Chemical Name:
Propargyl-PEG4-acid
Synonyms
Alkyne-PEG4-COOH;PROPARGYL-PEG4-COOH;Propargyl-PEG4-acid;Propargyl-PEG3-C2-COOH;Propargyl-PEG4-CH2CO2H;Propyne-PEG3-CH2CH2COOH;Propargyl-PEG3-CH2CH2COOH;4,7,10,13-tetraoxahexadec-15-ynoic acid;4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid;3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoic acid
CBNumber:
CB83048731
Molecular Formula:
C12H20O6
Molecular Weight:
260.28
MOL File:
1415800-32-6.mol
Modify Date:
2024/7/2 8:55:24

Propargyl-PEG4-acid Properties

Boiling point 388.0±37.0 °C(Predicted)
Density 1.129±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in Water, DMSO, DCM, DMF
pka 4.28±0.10(Predicted)
form Viscous Liquid
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02
Signal word  Danger
Hazard statements  H242
Precautionary statements  P210-P234-P235-P240-P370+P378-P403

Propargyl-PEG4-acid Chemical Properties,Uses,Production

Uses

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

Propargyl-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 68)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20296 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
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SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Propargyl-PEG4-acid Propargyl-PEG4-CH2CO2H Propyne-PEG3-CH2CH2COOH Alkyne-PEG4-COOH PROPARGYL-PEG4-COOH Propargyl-PEG3-CH2CH2COOH 4,7,10,13-tetraoxahexadec-15-ynoic acid 4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid Propargyl-PEG3-CH2CH2COOH/4,7,10,13-Tetraoxahexadec-15-ynoic acid Propargyl-PEG3-C2-COOH 3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoic acid 1415800-32-6 5800-32-6 peg