ChemicalBook > Product Catalog >Organic Chemistry >Alcohols,Phenols,Phenol alcohols >N-Boc-PEG6-alcohol

N-Boc-PEG6-alcohol

N-Boc-PEG6-alcohol Structure
CAS No.
331242-61-6
Chemical Name:
N-Boc-PEG6-alcohol
Synonyms
NHBoc-PEG6-OH;Boc-NH-PEG6-OH;BocNH-PEG6-alcohol;N-Boc-PEG6-alcohol;t-boc-N-amido-PEG6-alcohol;N-Boc-PEG6-alcohol,BocNH-PEG6-OH;17-(Boc-amino)-3,6,9,12,15-pentaoxa-1-heptadecanol;tert-Butyl(17-hydroxy-3,6,9,12,15-pentaoxaheptadecyl)carbamate;5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-hydroxy-, 1,1-dimethylethyl ester;2-[2-(2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethyl tert-butylcarbamate
CBNumber:
CB83062593
Molecular Formula:
C17H35NO8
Molecular Weight:
381.46
MOL File:
331242-61-6.mol
Modify Date:
2024/7/2 8:55:24

N-Boc-PEG6-alcohol Properties

Boiling point 487.1±45.0 °C(Predicted)
Density 1.087±0.06 g/cm3(Predicted)
solubility Soluble in DMSO, DCM, DMF
pka 12.23±0.46(Predicted)
form Viscous Liquid
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P261-P271
HS Code  2924190090

N-Boc-PEG6-alcohol Chemical Properties,Uses,Production

Uses

N-Boc-PEG6-alcohol is a PROTAC bridge that belongs to the PEG class and the Alkyl/ether class. N-Boc-PEG6-alcohol can be used to synthesize a series of PROTAC molecules from Chemicalbook. N-Boc-PEG6-alcohol is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs).

in vitro

PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaandforanE3ubiquitinligaseandtheotherisforthetargetprotein.PROTACsexploittheintracelChemicalbooklularubiquitin-proteasomesystemtoselectivelydegradetargetproteins.ADCsarecomprisedofanantibodytowhichisattachedanADCcytotoxinthroughanADClinker.

N-Boc-PEG6-alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 85)Suppliers
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N-Boc-PEG6-alcohol Boc-NH-PEG6-OH t-boc-N-amido-PEG6-alcohol N-Boc-PEG6-alcohol,BocNH-PEG6-OH 2-[2-(2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethyl tert-butylcarbamate NHBoc-PEG6-OH 17-(Boc-amino)-3,6,9,12,15-pentaoxa-1-heptadecanol tert-Butyl(17-hydroxy-3,6,9,12,15-pentaoxaheptadecyl)carbamate 5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-hydroxy-, 1,1-dimethylethyl ester BocNH-PEG6-OH/5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-hydroxy-, 1,1-dimethylethyl ester BocNH-PEG6-alcohol tert-butyl N-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate 331242-61-6 C17H35NO8 peg