N-azidoacetylmannosamine-tetraacylated

- CAS No.
- 361154-30-5
- Chemical Name:
- N-azidoacetylmannosamine-tetraacylated
- Synonyms
- N-azidoacetylmannosamine-tetraacylated (Ac4ManNAz);ManNAz tetraacetate;Ac4ManNAz (80% α isomer);Ac4ManNAz, 10 mM in DMSO;N-Azidoacetylmannosamine-tetraacylated;N-Azidoacetylmannosamine-tetraacylated 95%;N-Azidoacetylmannosamine-tetraacylated;1,3,4,6-Tetra-O-acetyl-N-azidoacetylmannosamine;Ac4ManNAz,N-Azidoacetylmannosamine-tetraacylated;1,3,4,6-Tetra-O-acetyl-N-azidoacetyl-D-mannosamine
- CBNumber:
- CB83364125
- Molecular Formula:
- C16H22N4O10
- Molecular Weight:
- 430.37
- MOL File:
- 361154-30-5.mol
- Modify Date:
- 2025/1/27 9:38:02
N-azidoacetylmannosamine-tetraacylated Chemical Properties,Uses,Production
Description
N-azidoacetylmannosamine-tetraacylated (Ac4ManNAz) is an unnatural azido-containing monosaccharide building block. The azide moiety can be used for modification though chemoselective ligation chemistries including CuAAC, Cu-free click reaction or Staudinger ligation. The acetyl groups increase solubility in many solvents and make handling of this reagent easier.
Application
N-Azidoacetylmannosamine-tetraacylated (Ac4ManNAz) is an azide-containing metabolic glycoprotein labeling reagent that can be incorporated into the sialic acid biosynthesis pathway. The azide-modified protein can be detected by reaction with alkynes. For example alkynes labeled with a fluorescent probe or a biotin can be used. The acetyl groups increase cell permeability and allow the unnatural sugars to easily pass through the cell membrane. Carboxyesterases remove the acetyl groups once the monosaccharide is in the cell.
Uses
Tetraacylated N-azidoacetylmannosamine is generally used in click chemistry applications in bioconjugate chemistry.
N-azidoacetylmannosamine-tetraacylated Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | China | 19805 | 58 | Inquiry |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 8497 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29808 | 58 | Inquiry |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 12186 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | China | 5975 | 58 | Inquiry |
Labnetwork lnc. | +86-27-50766799 +8618062016861 | China | 19987 | 58 | Inquiry |
Alfa Chemistry | United States | 24072 | 58 | Inquiry | |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6391 | 58 | Inquiry |
LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24727 | 58 | Inquiry |