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PICEATANNOL

PICEATANNOL Structure
CAS No.
10083-24-6
Chemical Name:
PICEATANNOL
Synonyms
Piceatanl;NSC-622471;PICEATANNOL;Astringenin;Beryl alcohol;20MG/50MG/100G;Piceatannol>Piceatannol,96%;(E)-Piceatannol;trans-Piceatannol
CBNumber:
CB8377487
Molecular Formula:
C14H12O4
Molecular Weight:
244.24
MOL File:
10083-24-6.mol
Modify Date:
2024/7/26 15:15:06

PICEATANNOL Properties

Melting point 223.0-227.0 °C
Boiling point 108°C/0.04mmHg(lit.)
Density 1.1245 (rough estimate)
refractive index 1.5190 (estimate)
storage temp. 2-8°C
solubility H2O: 0.5 mg/mL
form powder
pka 9.17±0.10(Predicted)
color light tan to yellow
λmax 323nm(MeOH)(lit.)
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
LogP 2.690 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
Safety Statements  24/25
WGK Germany  3
HS Code  29072990

PICEATANNOL price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P0453 Piceatannol powder 10083-24-6 5MG ₹35841.58 2022-06-14 Buy
Sigma-Aldrich(India) P0453 Piceatannol powder 10083-24-6 25MG ₹119572.95 2022-06-14 Buy
Sigma-Aldrich(India) 527948 Piceatannol - CAS 10083-24-6 - Calbiochem A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC 10083-24-6 1MG ₹8310 2022-06-14 Buy
TCI Chemicals (India) P1928 Piceatannol 10083-24-6 100MG ₹10800 2022-05-26 Buy
TCI Chemicals (India) P1928 Piceatannol 10083-24-6 1G ₹26000 2022-05-26 Buy
Product number Packaging Price Buy
P0453 5MG ₹35841.58 Buy
P0453 25MG ₹119572.95 Buy
527948 1MG ₹8310 Buy
P1928 100MG ₹10800 Buy
P1928 1G ₹26000 Buy

PICEATANNOL Chemical Properties,Uses,Production

Chemical Properties

yellow to golden or green crystalline powder

Uses

A human metabolite of Resveratrol (R150000). Piceatannol is strong anti-oxidant.

Definition

ChEBI: A stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5.

General Description

A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC50 = 3 μM), PKC (IC50 = 8 μM), MLCK (IC50 = 12 μM). In RBL-2H3 cells, the selective inhibition of Syk by piceatannol results in inhibition of FceR1-mediated signaling. Also inhibits wheat embryo Ca2+-dependent protein kinase (CDPK) (IC50 = 19 μM), and p72syk (IC50 = 10 μM), a non-receptor tyrosine kinase, relative to Lyn in isolated enzyme preparations. Also possesses anti-leukemic properties. Reported to activate sirtuins and promote the survival of eukaryotic cells.

Biological Activity

Anti-inflammatory, immunomodulatory and antiproliferative agent. Inhibits p56 lck and syk protein tyrosine kinases and inhibits TNF-induced NF- κ B activation and gene expression. Synthesis results from conversion of resveratrol (5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol ) by cytochrome P450 1B1.

Global( 363)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
XI'AN TIANGUANGYUAN BIOTECH CO., LTD. +86-029-86333380 18829239519 China 918 58 Inquiry
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Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21669 55 Inquiry

PICEATANNOL Spectrum

TRANS-3,3',4,5'-TETRAHYDROXYSTILBENE PICEATANNOL PICEATANNOL (3,3',4,5'-TETRAHYDROXY-TRAN (e)-4-[2-(3,5dihydroxyphenyl)ethenyl]1,2-benzenediol 4-[2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol trans-Piceatannol (E)-3,3',4,5'-Tetrahydroxystilbene (E)-Piceatannol Astringenin Piceatannol,96% Piceatannol3,4,3',5'-Tetrahydroxy-trans-stilbene Piceatanl 5-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]benzene-1,3-diol 20MG/50MG/100G (E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol (E)-3,3',4,5'-Stilbenetetrol 4-[(1E)-2-(3,5-DIHYDROXYPHENYL)ETHENYL]-1,2-BENZENEDIOL 3,3',4,5'-TETRAHYDROXYSTILBENE 3,3',4,5'-TETRAHYDROXY-TRANS-STILBENE 3,4,3',5'-TETRAHYDROXY-TRANS-STILBENE Piceatannol, (E)- Piceatannol - CAS 10083-24-6 - Calbiochem 1,2-Benzenediol,4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]- Piceatannol> Piceatannol ,>98% Resveratrol 3-Hydroxy Impurity Resveratrol Impurity 20 (trans-Piceatannol) NSC-622471 Piceatannol (Astringenin Beryl alcohol Piceatannol (6CI) trans-Piceatannol|||Astringenin 10083-24-6 Cell Signaling and Neuroscience BioChemical Lymphocyte Specific Kinase and Spleen Tyrosine Kinase (Lck, Syk) Kinase/Phosphatase Biology Non-Receptor Tyrosine Kinase Inhibitors Cell Biology Aromatics Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals chemical reagent pharmaceutical intermediate Protein Kinase Stilbenes (substituted) Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals Inhibitors Syk phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract