PICEATANNOL
- CAS No.
- 10083-24-6
- Chemical Name:
- PICEATANNOL
- Synonyms
- Piceatanl;NSC-622471;PICEATANNOL;Astringenin;Beryl alcohol;20MG/50MG/100G;Piceatannol>Piceatannol,96%;(E)-Piceatannol;trans-Piceatannol
- CBNumber:
- CB8377487
- Molecular Formula:
- C14H12O4
- Molecular Weight:
- 244.24
- MOL File:
- 10083-24-6.mol
- Modify Date:
- 2024/7/26 15:15:06
Melting point | 223.0-227.0 °C |
---|---|
Boiling point | 108°C/0.04mmHg(lit.) |
Density | 1.1245 (rough estimate) |
refractive index | 1.5190 (estimate) |
storage temp. | 2-8°C |
solubility | H2O: 0.5 mg/mL |
form | powder |
pka | 9.17±0.10(Predicted) |
color | light tan to yellow |
λmax | 323nm(MeOH)(lit.) |
Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months. |
LogP | 2.690 (est) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302+H312+H332 |
Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 |
Safety Statements | 24/25 |
WGK Germany | 3 |
HS Code | 29072990 |
PICEATANNOL price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | P0453 | Piceatannol powder | 10083-24-6 | 5MG | ₹35841.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P0453 | Piceatannol powder | 10083-24-6 | 25MG | ₹119572.95 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 527948 | Piceatannol - CAS 10083-24-6 - Calbiochem A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC | 10083-24-6 | 1MG | ₹8310 | 2022-06-14 | Buy |
TCI Chemicals (India) | P1928 | Piceatannol | 10083-24-6 | 100MG | ₹10800 | 2022-05-26 | Buy |
TCI Chemicals (India) | P1928 | Piceatannol | 10083-24-6 | 1G | ₹26000 | 2022-05-26 | Buy |
PICEATANNOL Chemical Properties,Uses,Production
Chemical Properties
yellow to golden or green crystalline powder
Uses
A human metabolite of Resveratrol (R150000). Piceatannol is strong anti-oxidant.
Definition
ChEBI: A stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5.
General Description
A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC50 = 3 μM), PKC (IC50 = 8 μM), MLCK (IC50 = 12 μM). In RBL-2H3 cells, the selective inhibition of Syk by piceatannol results in inhibition of FceR1-mediated signaling. Also inhibits wheat embryo Ca2+-dependent protein kinase (CDPK) (IC50 = 19 μM), and p72syk (IC50 = 10 μM), a non-receptor tyrosine kinase, relative to Lyn in isolated enzyme preparations. Also possesses anti-leukemic properties. Reported to activate sirtuins and promote the survival of eukaryotic cells.
Biological Activity
Anti-inflammatory, immunomodulatory and antiproliferative agent. Inhibits p56 lck and syk protein tyrosine kinases and inhibits TNF-induced NF- κ B activation and gene expression. Synthesis results from conversion of resveratrol (5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol ) by cytochrome P450 1B1.
PICEATANNOL Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 18829239519 | China | 918 | 58 | Inquiry |
Hebei Guanlang Biotechnology Co,.LTD | +86-19930503253; +8619930503252 | China | 5835 | 58 | Inquiry |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | China | 2989 | 58 | Inquiry |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20308 | 58 | Inquiry |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 | China | 346 | 58 | Inquiry |
Ouhuang Engineering Materials (Hubei) Co., Ltd | +86-86177 | China | 2901 | 58 | Inquiry |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16209 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
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