ANNEXIN-V-FLUOS
- CAS No.
- Chemical Name:
- ANNEXIN-V-FLUOS
- Synonyms
- ANNEXIN-V-FLUOS
- CBNumber:
- CB8411406
- Molecular Formula:
- Molecular Weight:
- 0
- MOL File:
- Mol file
- Modify Date:
- 2023/4/23 13:52:06
ANNEXIN-V-FLUOS Chemical Properties,Uses,Production
Uses
In the early stages of apoptosis, changes occur at the cell surface. One of these plasma membrane alterations is the translocation of phosphatidylserine (PS) from the inner part of the plasma membrane to the outer layer, by which PS becomes exposed at the external surface of the cell.
Annexin-V-FLUOS detects apoptotic cells in suspension cells using flow cytometry (FACS) or fluorescence microscopy, by binding to phosphatidylserine on the outer leaflet of apoptotic cell membranes. A simultaneous labeling with, e.g., propidium iodide (PI) is needed for differentiation of apoptotic from necrotic cells.
Other secondary labeling is possible, e.g., membrane surface staining with a phycoerythrin or TRITC-labeled monoclonal antibody for further cellular characterization.
General Description
Annexin-V-FLUOS is a phospholipid-binding protein with a high affinity for phosphatidylserine (PS). Detection of cell-surface PS with annexin-V thus serves as a marker for apoptotic cells. Analysis may be by flow cytometry or by fluorescence microscopy.
ANNEXIN-V-FLUOS Preparation Products And Raw materials
Raw materials
Preparation Products
ANNEXIN-V-FLUOS Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Roche Applied Science | 800 428 5433 | United States | 696 | 85 | Inquiry |
Shanghai Yanmu Industrial Co., Ltd. | 021-50760790 | CHINA | 6723 | 58 | Inquiry |
Shanghai Yupu Chemical Technology Co., Ltd. | 021-61842042 18964386050 | CHINA | 1328 | 58 | Inquiry |
Beijing Zhijie Fangyuan Technology Co., Ltd. | 010-82897201 15810200961 | CHINA | 6984 | 58 | Inquiry |
Shanghai Ziqi Biological Technology Co., Ltd. | 400-811-9081 13681619662 | CHINA | 6192 | 58 | Inquiry |
Shanghai Guduo Biological Technology Co., Ltd. | 021-58993001 | CHINA | 6266 | 58 | Inquiry |
Shanghai Yuanmu Biological Technology Co., Ltd. | 021-58322859 | CHINA | 6181 | 58 | Inquiry |
Shanghai Qiaoyu Biological Technology Co., Ltd. | 021-58999639 | CHINA | 6890 | 58 | Inquiry |
Beijing Bi Orange Blue Biotechnology Co., Ltd. | 15510022373 | CHINA | 6827 | 58 | Inquiry |
Shanghai Yuda Industrial Co., Ltd. | 021-64133189 13788995069 | CHINA | 6107 | 58 | Inquiry |