Apigenin 7-glucoside
- CAS No.
- 578-74-5
- Chemical Name:
- Apigenin 7-glucoside
- Synonyms
- COSMOSIIN;APIGETRIN;APIGENIN-7-O-GLUCOSIDE;COSMETIN;APIGENIN-7-GLUCOSIDE;Apigenin-7-O-β-D-glucoside;Apigenin-7-O-β-D-glucopyranoside;Apigenin-7-O-β-D-glucopyranoside;apigenin 7-O-β-D-glucoside;Cosmosioside
- CBNumber:
- CB8468248
- Molecular Formula:
- C21H20O10
- Molecular Weight:
- 432.38
- MOL File:
- 578-74-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:36
| Melting point | 230-237°C |
|---|---|
| Boiling point | 788.9±60.0 °C(Predicted) |
| Density | 1.642±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly, Sonicated), Methanol (Slightly) |
| pka | 6.13±0.40(Predicted) |
| form | Solid |
| color | Pale Yellow to Yellow |
| BRN | 65669 |
| Stability | Hygroscopic |
| InChIKey | KMOUJOKENFFTPU-YUVSVTSJNA-N |
| SMILES | C1(C2=CC=C(O)C=C2)OC2=C(C(=CC(OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C2)O)C(=O)C=1 |&1:17,20,22,24,r| |
| LogP | -0.040 (est) |
| CAS DataBase Reference | 578-74-5(CAS DataBase Reference) |
Apigenin 7-glucoside price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 44692 | Apigenin 7-glucoside analytical standard | 578-74-5 | 5MG | ₹21682.48 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR2199 | Apigenin-7-Glucoside Pharmaceutical Secondary Standard; Certified Reference Material | 578-74-5 | 75MG | ₹40940.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 44692 | Apigenin 7-glucoside analytical standard | 578-74-5 | 25MG | ₹86047.93 | 2022-06-14 | Buy |
Apigenin 7-glucoside Chemical Properties,Uses,Production
Definition
ChEBI: A glycosyloxyflavone that is apigenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
Application
Apigenin 7-glucoside is a flavonoid with anti-inflammatory and anxiolytic activities. It inhibits LPS-induced nitric oxide production in RAW 264.7 cells when used at concentrations ranging from 0.16 to 10 μM. In vivo, apigenin 7-glucoside (10 mg/kg) reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury. It also increases the number of entries and the time spent in the open arms of the elevated plus maze in rats, indicating anxiolytic activity.
Biological Functions
Apigenin 7-glucoside inhibited HL-60 cell growth, dose- and time-dependently, but did not cause apoptosis. The distribution of cells at different stages in the cell cycle indicated an accumulation of treated cells in the G2/M phase. Moreover, apigenin 7-glucoside induced granulocytic differentiation of HL-60 cells[1].
References
[1] Eri Nakazaki. “Proteomic study of granulocytic differentiation induced by apigenin 7-glucoside in human promyelocytic leukemia HL-60 cells.” European Journal of Nutrition 52 1 (2013): 25–35.
Apigenin 7-glucoside Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 267)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Jiangsu Yongjian Pharmaceutical Co.,Ltd | +86-0523-80183620 +86-17701422015 | China | 258 | 58 | Inquiry |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-19164747840 +86-13119157289 | China | 2969 | 58 | Inquiry |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | China | 1000 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860 +86-18080483897 | China | 3424 | 58 | Inquiry |
578-74-5(Apigenin 7-glucoside)Related Search:
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4H-1-Benzopyran-4-one,7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)
Apigenin 7-glucoside SynonyMs:Apigetrin
Apigenin 7-b-D-glucoside
4H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-
Apigenin 7-glucoside, >=98%
Apigetrin(Apigenin-7-O-glucoside)
5-Hydroxy-2-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
COSMIIN
7-O-BETA-D-GLUCOPYRANOSYLOXY-4',5-DIHYDROXYFLAVONE
7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 7- (.beta.-D-glucopyranosyloxy)-5-hydroxy-2-(4- hydroxyphenyl)-
APIGENIN-7-O-GLUCOSIDE WITH HPLC
Apigetrin, Cosmosiin
Apigenin 7-β-D-glucoside
4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)- (9ci)
7-o-(beta-D-Glucosyl)apigenin
Apigenin, 7-beta-D-glucopyranoside
Cosemetin
APIGENIN-7-GLUCOSIDE (COSMOSIIN)(P)
APIGENIN-7-O-GLUCOSIDE hplc
APIGENIN-7-O-GLUCOSIDE (COSMOSIIN)(P)
APIGENIN-7-O-GLUCOSIDE (COSMOSIIN)(SH)
Apigenin 7-glucoside, 98%, from Dendranthema indicum (L.) Des Moul.
5-hydroxy-2-(4-hydroxyphenyl)-7-[[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-4-one
Apigenin 7-glucoside, BR
Apigenin, 7-β-D-glucopyranoside
Apigenin 7-glucoside (Apigenin-7-O-β-D-glucopyranoside
Apigenin 7-glucoside CRS
Thalictiin
5-Hydroxy-2-(4-hydroxyphenyl)-7-((2S,3S,4S,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one
Apigenin 7-glucoside USP/EP/BP
5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
Apigetrin (Apigenin-7-O-β-D-glucopyranoside
7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-...
COSMETIN
COSMOSIIN
APIGENIN-7-O-GLUCOSIDE
APIGENIN-7-GLUCOSIDE
APIGETRIN
Cosmosioside
Apigenin-7-O-β-D-glucopyranoside
Apigenin-7-O-β-D-glucoside
apigenin 7-O-β-D-glucoside
Apigenin 7-O-β-glucoside
Apigenin-7-O-β-D-glucopyranoside
Apigenin 7-beta-D-glucoside
Cosmoside
578-74-5
Analytical Standards
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Alphabetic
Analytical Chromatography Product Catalog
chemical reagent
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
Pharmaceutical intermediate
Tri-substituted Flavones