2-bromo-4-chloropropiophenone
![2-bromo-4-chloropropiophenone Structure](CAS/GIF/877-37-2.gif)
- CAS No.
- 877-37-2
- Chemical Name:
- 2-bromo-4-chloropropiophenone
- Synonyms
- BCPP;Bupropion Impurity 32;2-bromo-4-chloropropiophenone;2-Bromo-1-(4-chlorophenyl)-1-propanone;1-Propanone, 2-bromo-1-(4-chlorophenyl)-;(2R)-2-bromo-1-(4-chlorophenyl)propan-1-one;2-Bromo-1-(4-chloro-phenyl)-propan-1-one, 2-Бром-1-(4-хлорфенил)-пропан-1-он, 2-bromo-4'-chloropropiophenone
- CBNumber:
- CB8947316
- Molecular Formula:
- C9H8BrClO
- Molecular Weight:
- 247.52
- MOL File:
- 877-37-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/13 17:03:25
Melting point | 77-79 °C(Solv: ligroine (8032-32-4)) |
---|---|
Boiling point | 296.7±15.0 °C(Predicted) |
Density | 1.518±0.06 g/cm3(Predicted) |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
color | Off-White to Pale Beige |
InChI | InChI=1S/C9H8BrClO/c1-6(10)9(12)7-2-4-8(11)5-3-7/h2-6H,1H3 |
InChIKey | SAKMPXRILWVZEG-UHFFFAOYSA-N |
SMILES | C(C1=CC=C(Cl)C=C1)(=O)C(Br)C |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H332-H335-H302-H315-H312-H319 |
Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P280-P302+P352-P312-P322-P363-P501 |
HS Code | 2914790090 |
2-bromo-4-chloropropiophenone Chemical Properties,Uses,Production
Uses
2-bromo-4-chloropropiophenone can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and chemical production processes.
Application
2-bromo-4-chloropropiophenone is an analytical reference standard categorized as a precursor in the synthesis of cathinones, including 4-chlorocathinone, 4-chloro-N, N-dimethylcathinone, 4-chloro-N-isopropylcathinone, 4-chloro-N-butylcathinone, 4-chloroethcathinone, and 4'-chloro-α-pyrrolidinopropiophenone. 2-Bromo-4'-chloropropiophenone is also a precursor in the synthesis of 4-chloromethcathinone.
Synthesis
A solution of 15.9 g (0.1 mol) of bromine in 20 ml of chloroform is added dropwise to a solution of 16.8 g (0.1 mol) of 4'-chloropropiophenone in 100 ml of chloroform, in the presence of a small amount of aluminium chloride, and the mixture is stirred overnight. After filtration and evaporation of the filtrate, the crystalline residue is washed with petroleum ether. When dry, it melts at 75° C.
2-bromo-4-chloropropiophenone Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
SANIKA CHEMICALS PVT.LTD. | +91-8422919852 +91-8422919852 | Mumbai, India | 38 | 58 | Inquiry |
Prash Intermediates | +91-9825106395 +91-9824179055 | Gujarat, India | 24 | 58 | Inquiry |
Vandana Chemicals | +91-9979898001 +91-9979898001 | Gujarat, India | 13 | 58 | Inquiry |
CHEMAZON LABORATORIES | +91 9848551964 | Hyderabad, India | 1320 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Vcare Medicines | 08046035803 | Mumbai, India | 114 | 58 | Inquiry |
Hebei Mojin Biotechnology Co.,Ltd | +8613288715578 | China | 438 | 58 | Inquiry |
Shanghai Worldyang Chemical Co.,Ltd. | ,+86-21-56795779; +8613651600618 | China | 1080 | 58 | Inquiry |
Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | China | 3582 | 58 | Inquiry |
Supplier | Advantage |
---|---|
SANIKA CHEMICALS PVT.LTD. | 58 |
Prash Intermediates | 58 |
Vandana Chemicals | 58 |
CHEMAZON LABORATORIES | 58 |
CLEARSYNTH LABS LTD. | 58 |
A.J Chemicals | 58 |
Vcare Medicines | 58 |
Hebei Mojin Biotechnology Co.,Ltd | 58 |
Shanghai Worldyang Chemical Co.,Ltd. | 58 |
Hebei Miaoyin Technology Co.,Ltd | 58 |
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