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2-bromo-4-chloropropiophenone

2-bromo-4-chloropropiophenone  Structure
CAS No.
877-37-2
Chemical Name:
2-bromo-4-chloropropiophenone
Synonyms
BCPP;Bupropion Impurity 32;2-bromo-4-chloropropiophenone;2-Bromo-1-(4-chlorophenyl)-1-propanone;1-Propanone, 2-bromo-1-(4-chlorophenyl)-;(2R)-2-bromo-1-(4-chlorophenyl)propan-1-one;2-Bromo-1-(4-chloro-phenyl)-propan-1-one, 2-Бром-1-(4-хлорфенил)-пропан-1-он, 2-bromo-4'-chloropropiophenone
CBNumber:
CB8947316
Molecular Formula:
C9H8BrClO
Molecular Weight:
247.52
MOL File:
877-37-2.mol
MSDS File:
SDS
Modify Date:
2024/6/13 17:03:25

2-bromo-4-chloropropiophenone Properties

Melting point 77-79 °C(Solv: ligroine (8032-32-4))
Boiling point 296.7±15.0 °C(Predicted)
Density 1.518±0.06 g/cm3(Predicted)
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color Off-White to Pale Beige
InChI InChI=1S/C9H8BrClO/c1-6(10)9(12)7-2-4-8(11)5-3-7/h2-6H,1H3
InChIKey SAKMPXRILWVZEG-UHFFFAOYSA-N
SMILES C(C1=CC=C(Cl)C=C1)(=O)C(Br)C

SAFETY

Risk and Safety Statements

2-bromo-4-chloropropiophenone Chemical Properties,Uses,Production

Uses

2-bromo-4-chloropropiophenone can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and chemical production processes.

Application

2-bromo-4-chloropropiophenone is an analytical reference standard categorized as a precursor in the synthesis of cathinones, including 4-chlorocathinone, 4-chloro-N, N-dimethylcathinone, 4-chloro-N-isopropylcathinone, 4-chloro-N-butylcathinone, 4-chloroethcathinone, and 4'-chloro-α-pyrrolidinopropiophenone. 2-Bromo-4'-chloropropiophenone is also a precursor in the synthesis of 4-chloromethcathinone.

Synthesis

A solution of 15.9 g (0.1 mol) of bromine in 20 ml of chloroform is added dropwise to a solution of 16.8 g (0.1 mol) of 4'-chloropropiophenone in 100 ml of chloroform, in the presence of a small amount of aluminium chloride, and the mixture is stirred overnight. After filtration and evaporation of the filtrate, the crystalline residue is washed with petroleum ether. When dry, it melts at 75° C.

2-bromo-4-chloropropiophenone Preparation Products And Raw materials

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SANIKA CHEMICALS PVT.LTD. +91-8422919852 +91-8422919852 Mumbai, India 38 58 Inquiry
Prash Intermediates +91-9825106395 +91-9824179055 Gujarat, India 24 58 Inquiry
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Hebei Miaoyin Technology Co.,Ltd +86-17367732028 +86-17367732028 China 3582 58 Inquiry
2-bromo-4-chloropropiophenone 2-Bromo-1-(4-chloro-phenyl)-propan-1-one, 2-Бром-1-(4-хлорфенил)-пропан-1-он, 2-bromo-4'-chloropropiophenone 1-Propanone, 2-bromo-1-(4-chlorophenyl)- 2-Bromo-1-(4-chlorophenyl)-1-propanone Bupropion Impurity 32 (2R)-2-bromo-1-(4-chlorophenyl)propan-1-one BCPP 877-37-2