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Triflumizole

Triflumizole Structure
CAS No.
99387-89-0
Chemical Name:
Triflumizole
Synonyms
Triumizole;Triflumizole;Triflumizole [iso];fungicide Triflumizole;Fruquintinib Impurity 15;Triumizole Solution, 1000ppm;N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine;(E)-1-(1-((4-Chloro-2-(trifluoromethyl)phenyl)imino)-2-propoxyethyl)-1H-imidazole;n-(4-Chloro-2-(trifluoromethyl)phenyl)-1-(1h-imidazol-1-yl)-2-propoxyethan-1-imine;4-Chloro-N-[(E)-1-(1H-imidazol-1-yl)-2-propoxyethylidene]-2-(trifluoromethyl)aniline
CBNumber:
CB91120821
Molecular Formula:
C15H15ClF3N3O
Molecular Weight:
345.75
MOL File:
99387-89-0.mol
Modify Date:
2024/7/24 13:33:21

Triflumizole Properties

vapor pressure 1.86 x 10-4 Pa (25 °C )
pka 3.7 (base)
Water Solubility 12.5 x 103 mg l-1(20 °C )
EPA Substance Registry System 1H-Imidazole, 1-[(1E)-1-[[4-chloro-2-(trifluoromethyl) phenyl]imino]-2-propoxyethyl]- (99387-89-0)

SAFETY

Risk and Safety Statements

RIDADR  3077
HazardClass  9
PackingGroup  III

Triflumizole Chemical Properties,Uses,Production

Uses

Triflumizole is used for the control of Gymnospurangum and Venturia spp. in pome fruit, against powdery Erysiphaceae in fruit and vegetables, and against Fusarium, Fulvia and Monilia spp. It is also used as a seed treatment against Helminthospurium, Tilletia and Ustilago spp. in cereals.

Metabolic pathway

Triflumizole is unstable in aqueous solution when exposed to light and it is readily metabolised by plants and animals. The primary route of metabolism is by cleavage of the imidazole ring to give several metabolites which retain the 4-chloro-2-trifluoromethylaniline moiety. The major metabolite in crops, 2, is formed by loss of the imidazole ring.

Degradation

Aqueous solutions of triflumizole are degraded by sunlight with a DT50 of 29 hours. The sole hydrolysis product of triflumizole in the dark is 2, which is formed by loss of the imidazole ring.
The major product of photolysis of triflumizole is 4, which is probably formed in the presence of oxygen via 3. This compound was soluble in the solid state but decomposed in solution, even if stored in a refrigerator (Hashimoto et al., 1990).

Triflumizole Preparation Products And Raw materials

Raw materials

Preparation Products

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Triumizole (E)-1-(1-((4-Chloro-2-(trifluoromethyl)phenyl)imino)-2-propoxyethyl)-1H-imidazole (E)-N-[4-Chloro-2-(trifluoromethyl)phenyl]-1-(1H-imidazol-1-yl)-2-(propyloxy)ethanimine 4-Chloro-N-[(E)-1-(1H-imidazol-1-yl)-2-propoxyethylidene]-2-(trifluoromethyl)aniline (E)-4-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-N-(1-IMIDAZOL-1-YL-2-PROPOXYETHYLIDENE)-O-TOLUIDINE Triflumizole [iso] Triflumizole Triumizole Solution, 1000ppm N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine fungicide Triflumizole Fruquintinib Impurity 15 n-(4-Chloro-2-(trifluoromethyl)phenyl)-1-(1h-imidazol-1-yl)-2-propoxyethan-1-imine 99387-89-0