QUERCETINPENTAACETATE
- CAS No.
- 1064-06-8
- Chemical Name:
- QUERCETINPENTAACETATE
- Synonyms
- Quercetin acetate;Pentaacetylquercetin;Quercetine pentaacetate;3,3',4',5,7-Pentaacetoxyflavone;3,3',4',5,7-Penta(acetyloxy)flavone;3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one;2-(3,4-diacetoxyphenyl)-4-oxo-4H-chromene-3,5,7-triyl triacetate;[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate;Quercetin pentaacetate,Respiratory syncytial virus,inhibit,Inhibitor,RSV;4H-1-Benzopyran-4-one, 3,5,7-tris(acetyloxy)-2-[3,4-bis(acetyloxy)phenyl]-
- CBNumber:
- CB91405559
- Molecular Formula:
- C25H20O12
- Molecular Weight:
- 512.42
- MOL File:
- 1064-06-8.mol
- Modify Date:
- 2023/5/21 10:59:17
QUERCETINPENTAACETATE Chemical Properties,Uses,Production
Description
Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in vitro (IC50 = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC50 = 20.2 μg/ml). Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC50 = 8.7 μM) and PGE2 production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM. It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC50s = 38, 25, and 58 μM, respectively).
Uses
[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.
QUERCETINPENTAACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
QUERCETINPENTAACETATE Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | China | 8739 | 58 | Inquiry |
TargetMol Chemicals Inc. | 4008200310 | China | 24016 | 58 | Inquiry |
Beijing Stronger Science Co., Ltd. | 0531-88924771 15614660963 | China | 10624 | 58 | Inquiry |
RD International Technology Co., Limited | 18024082417 | China | 9282 | 58 | Inquiry |
CHEMICAL LAND21 | 82- 2 -783 - 8063 | South Korea | 6315 | 74 | Inquiry |
Toronto Research Chemicals | +1 (416) 665-9696 | Canada | 6088 | 71 | Inquiry |
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