L-xylulose
- CAS No.
- 527-50-4
- Chemical Name:
- L-xylulose
- Synonyms
- L-XYLULOSE;laevo-xylulose;L-Xylulose ,98%;L-THREO-PENTULOSE;threo-2-pentulose;L-Threo-2-pentulose;Xanthone Impurity 18;L-threo-2-Pentulose (9CI);L-Xylulose (1.0 M in water);L-Xylulose - Aqueous solution
- CBNumber:
- CB9144310
- Molecular Formula:
- C5H10O5
- Molecular Weight:
- 150.13
- MOL File:
- 527-50-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/25 18:01:22
L-xylulose Chemical Properties,Uses,Production
Chemical Properties
L-xylulose is a clear liquid. It is a ketopentose, meaning that it has five carbon atoms and a ketogroup at carbon C-2. It has a molecular formula of C5H10O5 and a molar mass of 150.13 g/mol. Xylulose is almost colorless and it forms syrup. The formation of crystals has not been reported (Budavari, 1996). Both D- and L - enantiomers of xylulose are found as intermediates in metabolic pathways of prokaryotes as well as eukaryotes. Both forms are rare in nature (Doten and Mortlock, 1985b).
Uses
L-Xylulose is used in studies relating to potential inhibitors of glycosidases and has been proven to inhibit oligosaccharide processing to a degree.
Definition
ChEBI: L-xylulose is a xylulose. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is an enantiomer of a D-xylulose.
Application
L-Xylulose has been shown to be a specific inhibitor of certain α-glucosidases,while having virtually no effect on other glycosidases such as β-glucosidase or α- and β-mannosidases. Furthermore,it is a specific inhibitor of the N-linked glycoproteinprocessing enzyme，glucosidase I, but does not inhibit glucosidase I or otherglycoprotein processing mannosidases. Thus it could prove to be a useful inhibitor forstudying glycoprotein processing, especially as it has been proven to be non-toxic andto also be effective in cell cultures (Muniruzzaman et al., 1996). L-Xylulose has been shown to have a strong inhibitory effect on the a-glucosidases，sucrase and maltase, present in the small intestine. Thus, an L-xylulose containing drug preparation for reducing blood sugar levels in humans and animals has been patented (Heinz et al.,1998).
Preparation
In 1933 a synthetic procedure for producing small amounts of D- and L -xylulose was introduced. In this method D- or L-xylose is epimerized to the corresponding diastereomer. The isomerization of xylose in pyridine leads to the production of xylulose (Touster, 1962). This enzyme catalyzes the production of L-xylulose from xylitol using either PQQ (pyrroloquinoline quinone) or FAD (flavin adenine dinucleotide) as prosthetic group, and L-xylulose is accumulated in the medium (Adachi et al., 1999; Adachi et al., 2001).
L-xylulose Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | China | 4088 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | China | 5988 | 58 | Inquiry |
| Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046 | China | 5814 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
| Shanghai Hao Biological Technology Co., Ltd. | 021-58116080 18019263206 | CHINA | 6921 | 58 | Inquiry |
| Beijing Bomais Technology Development Co., Ltd. | 15210716102 | CHINA | 6573 | 58 | Inquiry |
| Shanghai Ziqi Biological Technology Co., Ltd. | 400-811-9081 13681619662 | CHINA | 6192 | 58 | Inquiry |
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