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Trimethyl orthobenzoate

Trimethyl orthobenzoate Structure
CAS No.
707-07-3
Chemical Name:
Trimethyl orthobenzoate
Synonyms
(Trimethoxymethyl)benzene;Methyl orthobenzoate;Benzene, (trimethoxymethyl)-;SKL283;NSC-67391;Orthobenzoate;trimethyl benzoate;Intedanib Impurity 6;TRIMETHYL-O-BENZOATE;Sunitinib Impurity 71
CBNumber:
CB9160297
Molecular Formula:
C10H14O3
Molecular Weight:
182.22
MOL File:
707-07-3.mol
MSDS File:
SDS
Modify Date:
2024/3/13 16:52:01

Trimethyl orthobenzoate Properties

Boiling point 87-88 °C/7 mmHg (lit.)
Density 1.061 g/mL at 25 °C (lit.)
refractive index n20/D 1.489(lit.)
Flash point 180 °F
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in organic solvents.
form Liquid
color Clear colorless
Sensitive Moisture Sensitive
BRN 777623
Stability Hygroscopic
InChIKey IECKAVQTURBPON-UHFFFAOYSA-N
CAS DataBase Reference 707-07-3(CAS DataBase Reference)
NIST Chemistry Reference Benzene, (trimethoxymethyl)-(707-07-3)
EPA Substance Registry System Benzene, (trimethoxymethyl)- (707-07-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39-37/39
WGK Germany  3
TSCA  Yes
HS Code  29163100
NFPA 704
2
2 1

Trimethyl orthobenzoate price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 164534 Trimethyl orthobenzoate 98% 707-07-3 10G ₹7252.75 2022-06-14 Buy
Sigma-Aldrich(India) 164534 Trimethyl orthobenzoate 98% 707-07-3 50G ₹33102.85 2022-06-14 Buy
ALFA India ALF-A10270-30 Trimethyl orthobenzoate, 98% 707-07-3 250g ₹19968 2022-05-26 Buy
ALFA India ALF-A10270-18 Trimethyl orthobenzoate, 98% 707-07-3 50g ₹14007 2022-05-26 Buy
TCI Chemicals (India) T2287 Trimethyl Orthobenzoate min. 95.0 % 707-07-3 5G ₹3200 2022-05-26 Buy
Product number Packaging Price Buy
164534 10G ₹7252.75 Buy
164534 50G ₹33102.85 Buy
ALF-A10270-30 250g ₹19968 Buy
ALF-A10270-18 50g ₹14007 Buy
T2287 5G ₹3200 Buy

Trimethyl orthobenzoate Chemical Properties,Uses,Production

Chemical Properties

clear colorless liquid

Uses

Trimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

General Description

Trimethyl orthobenzoate reacts with P-dimethylaminophosphonic acid bis(1-methylhydrazide) to yield 1,2,5,6-tetrahydro-1,5-dimethyl-6-(N,N-dimethylamino)-6-phenyl-1,2,4,5,6-tetrazaphosphorine-6-oxide.

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(trimethoxymethyl)-benzen (Trimethoxymethyl)benzene Methyl orthobenzoate Orthobenzoic acid, trimethyl ester Orthobenzoate Benzene, (trimethoxymethyl)- à,à,à-trimethoxytoluene Thrimethyl orthobenzoate Phenylorthoformic acid trimethyl ester Phenyltrimethoxymethane Trimethoxyphenylmethane Trimethyl orthobenzoate,97% alpha,alpha,alpha-Trimethoxytoluene Orthobenzoic Acid Trimethyl Ester alpha,alpha,alpha-Trimethoxytoluene Methyl Orthobenzoate Trimethyl orthobenzoate 98% NSC-67391 Intedanib Impurity 6 TRIMETHYL ORTHOBENZOATE TRIMETHYL-O-BENZOATE TriMethyl Orthobenzoate, 95%(GC) Trimethyl Orthobenzoate Liquid trimethyl benzoate SKL283 Trimethyl orthobenzoate (Nintedanib Impurity) Sunitinib Impurity 71 707-07-3 C6H5COCH33 Building Blocks Oxygen Compounds Organic Building Blocks Acetals/Ketals/Ortho Esters Acetals/Ketals/Ortho Esters Organic Building Blocks Oxygen Compounds bc0001 707-07-3