CAMPESTEROL
- CAS No.
- 474-62-4
- Chemical Name:
- CAMPESTEROL
- Synonyms
- Campesterin;Ergost-5-en-3-ol;24α-methyl Cholesterol;(24R)-Ergost-5-en-3β-ol;C01789;CAMPESTROL;CAMPESTEROL;Campasterol;Mieyajunsu A;-17-((2R,5R)
- CBNumber:
- CB9168763
- Molecular Formula:
- C28H48O
- Molecular Weight:
- 400.69
- MOL File:
- 474-62-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/25 18:01:22
| Melting point | 156-160 °C |
|---|---|
| alpha | D23 -33° (22.5 mg in 5 ml chloroform) |
| Boiling point | 463.29°C (rough estimate) |
| Density | 0.98±0.1 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5100 (estimate) |
| storage temp. | -20°C |
| solubility | Chloroform (Sparingly), Methanol (Slightly, Sonicated) |
| form | crystalline |
| pka | 15.03±0.70(Predicted) |
| color | white |
| Merck | 13,1736 |
| BRN | 3216975 |
| InChIKey | SGNBVLSWZMBQTH-ZRUUVFCLSA-N |
| LogP | 9.972 (est) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 |
| Hazard Codes | Xn,T |
| Risk Statements | 20/21/22-36/37/38-48/20/22-40-38-22 |
| Safety Statements | 26-36-45-36/37/39-23 |
| RIDADR | UN 1888 6.1/PG 3 |
| WGK Germany | 3 |
| HS Code | 29061990 |
CAMPESTEROL price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C5157 | Campesterol ~65% | 474-62-4 | 1MG | ₹10684.28 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C5157 | Campesterol ~65% | 474-62-4 | 5MG | ₹32864.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C5157 | Campesterol ~65% | 474-62-4 | 10MG | ₹58541.6 | 2022-06-14 | Buy |
CAMPESTEROL Chemical Properties,Uses,Production
Description
24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism. The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques. 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.
Chemical Properties
White Solid
Uses
Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.
General Description
Campesterol is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure.
Purification Methods
Campesterol is recrystallised twice from hexane and once from Me2CO. The benzoyl derivative has m 158-160o [] D 23 -8.6o (CHCl3), and the acetyl derivative has m 137138o (EtOH) and [] D 23 -35.1o (c 2.9, CHCl3) [Fernholz & MacPhillamy J Am Chem Soc 6 3 1155 1941]. [Beilstein 6 III 2680.]
CAMPESTEROL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21675 | 55 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9338 | 55 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3424 | 58 | Inquiry |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
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