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6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole Structure
CAS No.
1231930-33-8
Chemical Name:
6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole
Synonyms
6-Bromo-4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazole;Abemaciclib Impurity 1;Abemaciclib Impurity 1 D5;Abemaciclib Impurity 1 D12;6-bromo-4-fluoro-2-methyl-1-(1-methylethyl)-;6-Bromo-4-fluoro-1-isopropyl-2-methylbenzimidazole;6-bromo-4-fluoro-2-methyl-1-propan-2-ylbenzimidazole;6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzimidazole;6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole;6-bromo-4-fluoro-2-methyl-1-(propan-2-yl)-1H-1,3-benzodiazole
CBNumber:
CB92500134
Molecular Formula:
C11H12BrFN2
Molecular Weight:
271.13
MOL File:
1231930-33-8.mol
Modify Date:
2024/4/3 15:02:24
Request For Quotation

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole Properties

Boiling point 353.4±22.0 °C(Predicted)
Density 1.49
storage temp. Sealed in dry,Room Temperature
pka 3.48±0.10(Predicted)
InChI InChI=1S/C11H12BrFN2/c1-6(2)15-7(3)14-11-9(13)4-8(12)5-10(11)15/h4-6H,1-3H3
InChIKey SJQZRZLUEGCXFN-UHFFFAOYSA-N
SMILES C1(C)N(C(C)C)C2=CC(Br)=CC(F)=C2N=1

SAFETY

Risk and Safety Statements

HS Code  2933998090

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole Chemical Properties,Uses,Production

Uses

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole is a pharmaceutical intermediate. It can be used in the preparation of Abemaciclib, a kinase inhibitor for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer who have experienced disease progression following endocrine therapy and prior chemotherapy.

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole Preparation Products And Raw materials

Raw materials

1H-Benzimidazole, 5-bromo-7-fluoro-2-methyl- Ethanimidamide,N-(1-methylethyl)- EthaniMidaMide, N-(4-broMo-2,6-difluorophenyl)-N'-(1-Methylethyl)- 4-Bromo-2,6-difluoroaniline N-Isopropylacetamide
Acetone
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Preparation Products

1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)-

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole Suppliers

Global( 204)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BTC pharm India +918790379245 AndhraPradesh, India 1269 58 Inquiry
Shree Jaya Laboratories Pvt. Ltd. +91-91-40-29881167 +91-9966167167 Hyderabad, India 78 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20361 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21676 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Supplier Advantage
BTC pharm India 58
Shree Jaya Laboratories Pvt. Ltd. 58
SynZeal Research Pvt Ltd 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Henan Fengda Chemical Co., Ltd 58
Henan Tianfu Chemical Co.,Ltd. 55
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Chongqing Chemdad Co., Ltd 58

1231930-33-8(6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole)Related Search:

6-BroMo-4-fluoro-3-Methylindazole PERFLUOROPOLYALKYL ETHER GALDEN (TM) HT70 Hexafluoroisopropyl methyl ether 1H-BenziMidazole, 4-fluoro-2-Methyl-1-(1-Methylethyl)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
2-bromo-8-fluoro-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one PF-01367338 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine 4-(8-fluoro-6-oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)benzaldehyde 1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)-
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6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole 1H-BenziMidazole, 6-broMo-4-fluoro-2-Methyl-1-(1-Methylethyl)- 6-bromo-4-fluoro-2-methyl-1-propan-2-ylbenzimidazole 6-bromo-4-fluoro-2-methyl-1-(propan-2-yl)-1H-1,3-benzodiazole 6-Bromo-4-fluoro-1-isopropyl-2-methylbenzimidazole Abemaciclib Impurity 1 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole ISO 9001：2015 REACH Abemaciclib Impurity 1 D12 Abemaciclib Impurity 1 D5 6-Bromo-4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazole 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzimidazole 6-bromo-4-fluoro-2-methyl-1-(1-methylethyl)- 1231930-33-8 1230930-33-8 API