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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester

Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester

Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester Structure
CAS No.
27143-07-3
Chemical Name:
Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester
Synonyms
Ethyl chloro[(4-methoxyphenyl)hydrazono]acetate;(Z)-ethyl 2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate;Ethyl 2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate;Chloro[(4-methoxyphenyl)hydrazono]acetic acid ethyl ester;Ethyl(z)-2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate;hydrazono);Apixaban-2;Ethyl chloro;RSYY（Avanafil)-38;RSYY（Avanafil)-43
CBNumber:
CB92500866
Molecular Formula:
C11H13ClN2O3
Molecular Weight:
256.69
MOL File:
27143-07-3.mol
MSDS File:
SDS
Modify Date:
2024/5/18 8:51:57
Request For Quotation

Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester Properties

Melting point 94℃
Boiling point 349.0±44.0 °C(Predicted)
Density 1.23
storage temp. 2-8°C
solubility Chloroform (Sparingly), Methanol (Slightly)
form Solid
pka 11.63±0.10(Predicted)
color Yellow to Dark Yellow
InChI InChI=1S/C11H13ClN2O3/c1-3-17-11(15)10(12)14-13-8-4-6-9(16-2)7-5-8/h4-7,13H,3H2,1-2H3
InChIKey ATNPZEGMKLGIFA-UHFFFAOYSA-N
SMILES C(OCC)(=O)C(Cl)=NNC1=CC=C(OC)C=C1

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362

Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester Chemical Properties,Uses,Production

Physical properties

Light yellow to dark yellow solid

Uses

Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester is an ester derivative and can be used as an intermediate in the synthesis of apixaban.

Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester Preparation Products And Raw materials

Raw materials

p-Anisidine Ethyl 4-chloroacetoacetate

Preparation Products

Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester Suppliers

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27143-07-3(Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester)Related Search:

Apixaban Impurity 20 (4,4'‐didodecyl‐2,2'‐ bithiophene‐5,5'‐ diyl)bis(triMethylstann ane) 1-(4-Methoxyphenyl)-6-(4-(2-Methyl-6-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxaMide Apixaban Impurity 13 ETHYL (2E)-CHLORO[(4-CHLOROPHENYL)HYDRAZONO]ACETATE
1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid Apixaban IMpurity 3 1-(4-chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxaMide Apixaban Impurity 11 Apixaban IMpurity 5 (BMS-591329-01)
3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one 1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester 1-(4-Nitrophenyl)-2-piperidinone
4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-[4-(5-methyl-2-oxo-1-piperidinyl)phenyl]-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl (R)-3-Piperidinamine dihydrochloride
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2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene] (Z)- Ethyl chloro[(4-Methoxyphenyl)hydrazono]acetate Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester 2-chloro-2-[2-(4-Methoxyphenyl)hydrazinylidene], ethyl ester ethyl chloro[2-(4-Methoxyphenyl)hydrazinylidene]acetate thyl chloro[2-(4-methoxyphenyl)hydrazinylidene]acetate Chloro((4-Methoxyphenyl)hydrazone)acetic acid ethyl ester 1. 2-chloro-2-[2-(4-Methoxyphenyl)hydrazinylidene]acetic acid ethyl ester 2-chloro-2-[2-(4-Methoxyphenyl)hydrazinylidene] acetic acid, ethyl ester Ethyl chloro[(4-methoxyphenyl)hydrazono]acetate Chloro[(4-methoxyphenyl)hydrazono]acetic acid ethyl ester ethyl (2Z)-2-chloro-2-[(4-methoxyphenyl)hydrazinylidene]acetate Apixaban Intermediate 1 Ethyl 2-chloro-2-(2-(4-methoxyphenyl) hydrazono) ethyl 2-chloro-2-[(4-methoxyphenyl)hydrazinylidene]acetate Apixaban Impurity B (Z)-Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (Apixaban) Apixaban-2 1-(4-methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxamide Acetic acid, chloro[(4-methoxyphenyl)hydrazono]-, ethyl ester ethyl 7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate，Aceticacid,2-chloro-2-[2-(4- methoxyphenyl)hydrazinylidene], ethyl ester Apixaban intermediates，Ethyl chloro[2-(4- methoxyphenyl)hydrazinylidene]acetate Apixaban ethyl chloroacetate Apixaban Impurity 158 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene] Apixaban Impurity 18 Ethyl 2-chloro-2-(2 -(4-methoxyphenyl)hydrazono)acetate chloro ester ethyl 2-chloro-2-[(4-methoxyphenyl)hydrazono]acetate Impurity of apixaban382 Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl este Chloro[(4-methoxyphenyl)hydrazono]acetic acid ethyl ester Ethyl chloro[(4-methoxyphenyl)hydrazono]acetate Ethyl 2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate (Z)-ethyl 2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate Ethyl(z)-2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate Aceticacid,2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene]-,ethylester,(8Z)- RSYY（Avanafil)-38 RSYY（Avanafil)-43 Ethyl [(4-methoxyphenyl)hydrazono]chloroacetate Ethyl chloro (Z)-Ethyl-2-C-2-(2-(4-Methoxy Phenyl) Hydrazone acetate Ethyl chloro[(4-methoxyphenyl)hydrazono]acetat Ethyl 2-chloro-2-[2-(4-methyoxyphenyl)hydrazono]acetate Apixaban Impurity 2 27143-07-3 27143-07-0 27143-07-2 27143-07-3