CATHEPSIN D
- CAS No.
- 9025-26-7
- Chemical Name:
- CATHEPSIN D
- Synonyms
- EC 3.4.23.5;EC 3.4.22.5;CATHEPSIN D;Cathepsins D;CATHEPSIN D, HUMAN;CATHEPSIN D, BOVINE;CATHEPSIN D, HUMAN LIVER;Native Human Cathepsin D;CATHEPSIN D, HUMAN SPLEEN;Native Bovine Cathepsin D
- CBNumber:
- CB9265367
- Molecular Formula:
- NULL
- Molecular Weight:
- 0
- MOL File:
- Mol file
- Modify Date:
- 2023/4/23 13:52:06
CATHEPSIN D price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C3138 | Cathepsin D from bovine spleen lyophilized powder, ≥2.0?units/mg protein | 9025-26-7 | 5UNITS | ₹25086 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C3138 | Cathepsin D from bovine spleen lyophilized powder, ≥2.0?units/mg protein | 9025-26-7 | 10UNITS | ₹41436.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C3138 | Cathepsin D from bovine spleen lyophilized powder, ≥2.0?units/mg protein | 9025-26-7 | 20UNITS | ₹82650.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C8696 | Cathepsin D from human liver lyophilized powder, ≥250?units/mg protein (E1%/280) | 9025-26-7 | 25μG | ₹32667.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C3138 | Cathepsin D from bovine spleen lyophilized powder, ≥2.0?units/mg protein | 9025-26-7 | 40UNITS | ₹153990.3 | 2022-06-14 | Buy |
CATHEPSIN D Chemical Properties,Uses,Production
Uses
Cathepsin D, human liver is useful for inhibitor screening, kinetic studies, and cleavage of substrates in vitro or in tissue culture. It contains the mannose-6-phosphate lysosomal localization signal that targets the enzyme to the lysosomal compartment where it functions in the normal degradation of proteins. It is a useful prognostic indicator for breast cancer.
General Description
Cathepsin D is an aspartic protease, which is located in lysosomes. It is involved in protein catabolism and maintains hormone and antigen processing. Cathepsin D is implicated in neoplasia and neurodegenerative changes. It regulates lysosomal proteolysis and endogenous fibrinolysis.
Purification Methods
Cathepsin D is purified on a CM column after (NH4)2SO4 fractionation and dialysis, then starch-gel electrophoresis and by ultracentrifugal analysis. Finally chromatograph on a DEAE column [Press et al. Biochem J 74 501 1960].
CATHEPSIN D Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| EMD Biosciences, Inc. | 858 450 5500 | United States | 6529 | 66 | Inquiry |
| VWR International | 800 932 5000 | United Kingdom | 6554 | 82 | Inquiry |
| BIOTREND Chemikalien GmbH | 49 (0) 221 949 83 20 | Germany | 6115 | 76 | Inquiry |
| SIGMA-RBI | 800 736 3690 (Orders) | Switzerland | 6913 | 91 | Inquiry |
| MP Biomedicals, Inc. | 949 833 2500 | United States | 6566 | 81 | Inquiry |
| Kanto Chemical Co., Inc. | +81 3 3663 7631 | Japan | 6762 | 74 | Inquiry |
| Cortex Biochem, Inc. | 510 568 2228 | United States | 1557 | 77 | Inquiry |
| BIODESIGN International/OEM Concepts | 888 530 0140 | United States | 2376 | 50 | Inquiry |
| A.T.CHEMICAL | 0755-86655561 81899190 | China | 6594 | 51 | Inquiry |
| kemikalieimport | + 45 - 2034 3359 | Europe | 6699 | 47 | Inquiry |
| Supplier | Advantage |
|---|---|
| EMD Biosciences, Inc. | 66 |
| VWR International | 82 |
| BIOTREND Chemikalien GmbH | 76 |
| SIGMA-RBI | 91 |
| MP Biomedicals, Inc. | 81 |
| Kanto Chemical Co., Inc. | 74 |
| Cortex Biochem, Inc. | 77 |
| BIODESIGN International/OEM Concepts | 50 |
| A.T.CHEMICAL | 51 |
| kemikalieimport | 47 |
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