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(2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid

(2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid Structure
CAS No.
59969-65-2
Chemical Name:
(2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid
Synonyms
Z-(2S,3R)-AHPA;Z-(2R,3S)-AHPA;(2S,3R)-3-(Cbz-amino)-2-hydroxy-4-phenylbutanoic Acid;2S,3R)-3-(((benzyloxy)carbonyl)-Amino)-2-hydroxy-4-phenylbutyric acid;(2R,3S)-3-(((benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid;(2S,3R)-3-(((benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid;Benzenebutanoic acid, α-hydroxy-β-[[(phenylmethoxy)carbonyl]amino]-, (αS,βR)-;(alphaS,betaR)-alpha-Hydroxy-beta-[[(phenylmethoxy)carbonyl]amino]benzenebutanoic acid
CBNumber:
CB92655481
Molecular Formula:
C18H19NO5
Molecular Weight:
329.35
MOL File:
59969-65-2.mol
Modify Date:
2023/5/12 16:02:16
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(2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid Properties

Melting point 152-153 °C
Boiling point 581.9±50.0 °C(Predicted)
Density 1.295±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 3.56±0.17(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid Chemical Properties,Uses,Production

Biological Activity

(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyric acid (AHPA) derivatives are used as inhibitors of enkephalinase(s) to augment met5-enkephalin-induced anti-nociception. The derivative (2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl-L-valine (AHPA-Val) is used as a bestatin analogue.

Synthesis

(2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid is prepared by Hydrogenolysis of Methyl (αS,βR)-α-hydroxy-β-[[(phenylmethoxy)carbonyl]amino]benzenebutanoate with Sodium hydroxide in 1,4-Dioxane.

(2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid Preparation Products And Raw materials

Raw materials

Benzenebutanoic acid, α-hydroxy-β-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (αS,βR)-

Preparation Products

(2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid Suppliers

Global( 36)Suppliers
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A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
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Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10978 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Shanghai XueEr Pharmaceutical Technology Co., Ltd 021-34622192 13917187091 China 75 57 Inquiry
Supplier Advantage
A.J Chemicals 58
career henan chemical co 58
Chongqing Chemdad Co., Ltd 58
Shaanxi Dideu Medichem Co. Ltd 58
Baoji Guokang Healthchem co.,ltd 58
Labnetwork lnc. 58
Chengdu Hepu Pharmaceutical Technology Co. , Ltd 58
Zibo Hangyu Biotechnology Development Co., Ltd 58
Amadis Chemical Company Limited 58
Shanghai XueEr Pharmaceutical Technology Co., Ltd 57

59969-65-2((2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid)Related Search:

Ubumex capsule Branched Chain
(2R,3S)-3-(((benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid Z-(2R,3S)-AHPA (alphaS,betaR)-alpha-Hydroxy-beta-[[(phenylmethoxy)carbonyl]amino]benzenebutanoic acid Z-(2S,3R)-AHPA 2S,3R)-3-(((benzyloxy)carbonyl)-Amino)-2-hydroxy-4-phenylbutyric acid Benzenebutanoic acid, α-hydroxy-β-[[(phenylmethoxy)carbonyl]amino]-, (αS,βR)- (2S,3R)-3-(((benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid (2S,3R)-3-(Cbz-amino)-2-hydroxy-4-phenylbutanoic Acid 59969-65-2