N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester

N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester Structure
CAS No.
1332524-01-2
Chemical Name:
N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester
Synonyms
Methyl 2-((3-fluoro-4-(MethylcarbaMoyl)phenyl)aMino)-2-Methylpropanoate;Enzalutamide Impurity 60;Enzalutamide Impurity 32;2-{[3-fluoro-4-(methylcarbamoyl)phenyl]amino}-2-methylpropanoate;methyl 2-[3-fluoro-4-(methylcarbamoyl)anilino]-2-methyl-propanoat e;N-[3-fluoro-4-[(methylamino) carbonyl]benzene Subunit]-2-Methyl alanine;2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate methyl;N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester;NN-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester;Alanine, N-[3-fluoro-4-[(MethylaMino)carbonyl]phenyl]-2-Methyl-, Methyl ester
CBNumber:
CB92657809
Molecular Formula:
C13H17FN2O3
Molecular Weight:
268.28
MOL File:
1332524-01-2.mol
MSDS File:
SDS
Modify Date:
2024/5/6 18:26:58

N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester Properties

Boiling point 381℃
Density 1.203
Flash point 184℃
solubility Chloroform, DCM, Ethyl Acetate
pka 14.35±0.46(Predicted)
form Solid
color White

N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester Chemical Properties,Uses,Production

Uses

N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine Methyl Ester is an intermediate in the synthesis of MDV 3100 (M199800), is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex.

N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Alanine, N-[3-fluoro-4-[(MethylaMino)carbonyl]phenyl]-2-Methyl-, Methyl ester N-[3-fluoro-4-[(MethylaMino)carbonyl]phenyl]-2-Methyl-Alanine Methyl ester 2-(3-Fluoro-4-MethylcarbaMoyl-phenylaMino)-2-Methyl-propionic acid Methyl ester " N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate methyl NN-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester methyl 2-[3-fluoro-4-(methylcarbamoyl)anilino]-2-methyl-propanoat e Enzalutamide Impurity 32 Methyl 2-((3-fluoro-4-(MethylcarbaMoyl)phenyl)aMino)-2-Methylpropanoate N-[3-fluoro-4-[(methylamino) carbonyl]benzene Subunit]-2-Methyl alanine Enzalutamide Impurity 60 2-{[3-fluoro-4-(methylcarbamoyl)phenyl]amino}-2-methylpropanoate 1332524-01-2