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1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate Structure
CAS No.
56602-33-6
Chemical Name:
1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate
Synonyms
BOP;BOP REAGENT;BENZOTRIAZOL-1-YLOXYTRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE;1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate [Coupling Reagent for Peptide];cas:56602-33-6;BOP-reaagent;CASTROS REAGENT;CASTRO'S REAGENT;BOP Reagent(BOP);BOP, Castros Reagent
CBNumber:
CB9434718
Molecular Formula:
C12H22F6N6OP2
Molecular Weight:
442.29
MOL File:
56602-33-6.mol
MSDS File:
SDS
Modify Date:
2023/8/16 12:01:05

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate Properties

Melting point >130 °C (dec.)(lit.)
Flash point 138°C
storage temp. 2-8°C
solubility methanol: 25 mg/mL, clear
form Powder
color White to off-white
Water Solubility Soluble in methanol, acetone and dichloromethane. Insoluble in water.
Sensitive Moisture & Light Sensitive
Decomposition 138 ºC
BRN 4287025
CAS DataBase Reference 56602-33-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H228-H315-H335
Precautionary statements  P210-P240-P241-P261-P264-P302+P352
Hazard Codes  Xi,E,F
Risk Statements  37/38-44-36/37/38-11-2
Safety Statements  24/25-37/39-36-26-35-36/37/39
RIDADR  UN 1325 4.1/PG 2
WGK Germany  3
8-10-21
Hazard Note  Irritant
HazardClass  4.1
PackingGroup 
HS Code  29339980
NFPA 704
2
2 1

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 8.51004 BOP Benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorophosphate Novabiochem? 56602-33-6 25G ₹6570 2022-06-14 Buy
Sigma-Aldrich(India) 8.51004 BOP Benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorophosphate Novabiochem? 56602-33-6 100G ₹21800 2022-06-14 Buy
Sigma-Aldrich(India) 226084 (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate 97% 56602-33-6 1G ₹1667.05 2022-06-14 Buy
Sigma-Aldrich 226084 (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate 97% 56602-33-6 5G ₹2478.93 2022-06-14 Buy
Sigma-Aldrich(India) 226084 (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate 97% 56602-33-6 5G ₹2478.93 2022-06-14 Buy
Product number Packaging Price Buy
8.51004 25G ₹6570 Buy
8.51004 100G ₹21800 Buy
226084 1G ₹1667.05 Buy
226084 5G ₹2478.93 Buy
226084 5G ₹2478.93 Buy

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate Chemical Properties,Uses,Production

Chemical Properties

white to off-white powder

Uses

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate is a peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.

Purification Methods

Dissolve it in CH2Cl2, dry (MgSO4), filter, concentrate it under a vacuum, then add dry Et2O and filter off the first crop. Add CH2Cl2 to the filtrate and concentrate again to obtain a second crop. The solid is washed with dry Et2O and dried in a vacuum. Also recrystallise it from dry Me2CO/Et2O and check the purity by NMR. Store it in the dark. [Castro et al. Synthesis 751 1976, Nguyen et al J Chem Soc, Perkin Trans I 1915 1987, Coste et al. Tetrahedron Lett 36 4253 1995.]

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate Preparation Products And Raw materials

Global( 435)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
NSJ Prayog Life Sciences Private Limited +91-6281747900 +91-6281747900 Hyderabad, India 76 58 Inquiry
ADVENT CHEMBIO PRIVATE LIMITED +91-9821524116 +91-9821524116 Mumbai, India 353 58 Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
Sisco Resech Laboratories Private Limited +91-22-4268 5800 Mumbai, India 655 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
BENZOTRIAZOLYL-N-OXY-TRIS(DIMETHYL-AMINO )PHOSPHONI Benzotriazole-1-yl-o BOP, Castros Reagent (1H-Benzo[d][1,2,3]triazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate(V) BENZOTRIAZOLYL-N-OXYTRIS-(DIMETHYLAMINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE) BENZOTRIAZOLE-1-YL-OXY-TRIS-DIMETHYLAMINOPHOPHONIUM BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOSPHONIUM HEXAFLUOROPHOSPHATE BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOSPHONIUM BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOPHONIUM HEXAFLUOROPHOSPHATE CASTROS REAGENT CASTRO'S REAGENT HEXAFLUOROPHOSPHATE BOP BENZOTRIAZOL-1-YLOXYTRIS(DIMETHYLAMINO)- PHOSPHONIUM HEXAFLUOROPHOSPHATE, 97 BENZOTRIAZOLYL-N-OXY-TRIS(DIMETHYL-*AMINO)PHOSPHONIU BOP REAGENT:BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOSPHONIUM HEXAFLUOROPHOSPHATE BOP [BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE] Benzotriazol-1-yloxytris(dimethylamino)phosphonium Benzotriazol-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorphosphate(BOP) Benzotriazol-1-yloxytris(dimethylamino)-phosphonium hexafluorophosphate, 98+% BOP BENZOTRIAZOL-1-YLOXY)TRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE BOP reagent, 99% min. BENZOTRIAZOL-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOSPHONIUM HEXAFLUORPHOSPHATE Tri(dimethylamino)benzotriazol-1-yloxyphosphonium hexafluorophosphate BOP(Benzotriazol-1-yl-tris(diMethylaMinophosphoniuM hexafluorophosphate) Six fluoride phosphate three benzotriazole - 1 - oxygen radicals (diMethyl aMine) phosphorus (56602-33-6) carter condensing agent 700 g Cartercondensation agent (Benzotriazol-1-yloxy)tris(diMethylaMino)phosphoniuM hexafluorophosphate 97% Phosphorus(1+), [1-(hydroxy-κO)-1H-benzotriazolato]tris(N-methylmethanaminato)-, (T-4)-, hexafluorophosphate(1-) Benzotriazol-1-yl-oxy-tris(dimethylamino)phosphonium hexafluorophosphate≥ 98% (HPLC) BOP Benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorophosphate Novabiochem BOP hexafluorophosphate 1H-BENZOTRIAZOL-1-YLOXYTRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE (1-hydroxy-1h-benzotriazolato-o)tris(n-methylmethanaminato)-phosphorus(1++ benzotriazol-1-yl-oxytris(dimethylamino)phosphoniumhexa-fluorophosphate(bop) BOP, BENZOTRIAZO-1-YLOXY-TRIS[DIMETHYLAMINO]PHOSPHONIUM HEXAFLUOROPHOSPHATE BENZOTRIAZOL-1-YL-OXY-TRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE (BOP REAGENT) benzotriazol-1-yloxytris(dimethylamino)phosphonium PF6 BOP Reagent, BOP, Castros reagent Phosphorus(1+), (1-hydroxy-1H-benzotriazolato-O)tris(N-methylmethanaminato)-, (T-4)-, hexafluorophosphate(1-) Benzotriazol-1-yl-oxy-tris(dimethylamino)phosphonium hexafluorop BENZOTRIAZOLYL-N-OXYTRIS-(DIMET BOP-reaagent Benzotriazol-1-yloxytris(dimethylamino)-phosphonium hexafluorophosp BOP Reagent(BOP) 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate [Coupling Reagent for Peptide]> Benzotriazol-1-yloxytris(dimethylamino)-phosphonium hexafluorophosphate, 98%, for synthesis BOP Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate,98% Benzotriazol-1-yloxyphosphonium hexafluorophosphate Benzotriazole -1- oxytris (dimethylamino) - hexafluorophosphoric acid PHOSPH 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate USP/EP/BP tri(dimethylamino)benzotriazol-1-yloxyphosphonium hexafluoro... BOP(CAS# 56602-33-6) BOP Reagent extrapure AR, 98% benzotriazol-1-yloxy-tris(dimethylamino)phosphanium BENZOTRIAZOL-1-YLOXYTRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE BOP REAGENT BOP 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate [Coupling Reagent for Peptide]