ChemicalBook > Product Catalog >Biochemical Engineering >nucleic acid drugs >6-METHYLAMINOPURINE 9-RIBOFURANOSIDE

6-METHYLAMINOPURINE 9-RIBOFURANOSIDE

6-METHYLAMINOPURINE 9-RIBOFURANOSIDE Structure
CAS No.
1867-73-8
Chemical Name:
6-METHYLAMINOPURINE 9-RIBOFURANOSIDE
Synonyms
N6-Me-A;CS-1297;N6-Me-rA;N6-Me-Ar;NSC-29409;N6-Me-Adenosine;N-Methyladenosine;Adenosine, N-methyl-;N6,N6-Methyladenosin;Adenosine Impurity 15
CBNumber:
CB9503892
Molecular Formula:
C11H15N5O4
Molecular Weight:
281.27
MOL File:
1867-73-8.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:42

6-METHYLAMINOPURINE 9-RIBOFURANOSIDE Properties

Melting point 172 °C
Boiling point 649.1±65.0 °C(Predicted)
Density 1.85±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form Powder
pka 13.12±0.70(Predicted)
color White to off-white
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
NFPA 704
0
2 0

6-METHYLAMINOPURINE 9-RIBOFURANOSIDE Chemical Properties,Uses,Production

Description

N6-Methyladenosine is an adenosine analog. It inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta when used at a concentration of 10 μM. N6-Methyladenosine (1 mg/kg, i.v.) decreases arterial blood pressure and renal blood flow and increases peripheral resistance in anesthetized dogs. It also inhibits tumor growth in the C3H/ST and C3HB/ST mouse models of spontaneous mammary adenocarcinomas. N6-Methyladenosine is also the most prevelant mRNA modification in eukaryotes and has roles in cell viability and development.

Uses

N6-Methyladenosine is the most common internal modification of eukaryotic mRNA. The result of this modification is specifically recognized mRNA in the cytoplasm which regulates mRNA stability.N6-Methyladenosine is made when a protein complex containin the writer enzyme METTL3 adds a methyl group to adenosine. Two different eraser enzymes ALKBH5 and FTO can remove a methyl group to turn m6A bach into adenosine.

Definition

ChEBI: A methyladenosine compound with one methyl group attached to N6 of the adenine nucleobase.

6-METHYLAMINOPURINE 9-RIBOFURANOSIDE Preparation Products And Raw materials

Global( 151)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Gagri Global IT Services Pvt. Ltd. +91-40-27170174, Telangana, India 1321 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
Jinan Carbotang Biotech Co.,Ltd. +8615866703830 China 7353 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Fuxin Pharmaceutical +86-021-021-50872116 +8613122107989 China 10297 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Zhengzhou Alfa Chemical Co.,Ltd +8618530059196 China 13127 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
NSC-29409 6-Methylaminopurine D-riboside 6-Methylaminopurine ribonucleoside 6-Methylaminopurinosine Adenosine, N-methyl- (2R,3S,4R,5R)-2-(HydroxyMethyl)-5-(6-(MethylaMino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol N6-methyladenosine (m6A) N6-Me-rA N6-Me-A 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-methylaminopurin-9-yl)oxolane-3,4-diol N-Methyladenosine CS-1297 Adenosine Impurity 15 2-(hydroxymethyl)-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol N6,N6-Methyladenosin N6-Me-Adenosine N6-Me-Ar N6-Methyladenosine RNA-modified nucleoside m6A N-6-methyladenosine,inhibit,N6-Methyladenosine,Inhibitor,Endogenous Metabolite,N6methyladenosine,N6 methyladenosine,Influenza Virus RNA-modified nucleoside m6A 1867-73-8 Inhibitors