6-METHYLAMINOPURINE 9-RIBOFURANOSIDE

- CAS No.
- 1867-73-8
- Chemical Name:
- 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE
- Synonyms
- N6-Me-A;CS-1297;N6-Me-rA;N6-Me-Ar;NSC-29409;N6-Me-Adenosine;N-Methyladenosine;Adenosine, N-methyl-;N6,N6-Methyladenosin;Adenosine Impurity 15
- CBNumber:
- CB9503892
- Molecular Formula:
- C11H15N5O4
- Molecular Weight:
- 281.27
- MOL File:
- 1867-73-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/17 16:00:36
Melting point | 172 °C |
---|---|
Boiling point | 649.1±65.0 °C(Predicted) |
Density | 1.85±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
form | Powder |
pka | 13.12±0.70(Predicted) |
color | White to off-white |
PH | 4.0 |
λmax | 262 (pH 1);266 (pH 7) |
Stability | Hygroscopic |
6-METHYLAMINOPURINE 9-RIBOFURANOSIDE Chemical Properties,Uses,Production
Description
N6-Methyladenosine is an adenosine analog. It inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta when used at a concentration of 10 μM. N6-Methyladenosine (1 mg/kg, i.v.) decreases arterial blood pressure and renal blood flow and increases peripheral resistance in anesthetized dogs. It also inhibits tumor growth in the C3H/ST and C3HB/ST mouse models of spontaneous mammary adenocarcinomas. N6-Methyladenosine is also the most prevelant mRNA modification in eukaryotes and has roles in cell viability and development.
Uses
N6-Methyladenosine is the most common internal modification of eukaryotic mRNA. The result of this modification is specifically recognized mRNA in the cytoplasm which regulates mRNA stability.N6-Methyladenosine is made when a protein complex containin the writer enzyme METTL3 adds a methyl group to adenosine. Two different eraser enzymes ALKBH5 and FTO can remove a methyl group to turn m6A bach into adenosine.
Definition
ChEBI: A methyladenosine compound with one methyl group attached to N6 of the adenine nucleobase.
6-METHYLAMINOPURINE 9-RIBOFURANOSIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
Gagri Global IT Services Pvt. Ltd. | +91-40-27170174, | Telangana, India | 1321 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29858 | 58 | Inquiry |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 8497 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19552 | 58 | Inquiry |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | China | 9642 | 58 | Inquiry |
NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | China | 9985 | 58 | Inquiry |
1867-73-8(6-METHYLAMINOPURINE 9-RIBOFURANOSIDE)Related Search:
1of4
chevron_right