2-ブロモ-5-フルオロアニリン
2-ブロモ-5-フルオロアニリン 物理性質
- 融点 :
- 43-47 °C (lit.)
- 沸点 :
- 154 °C / 23mmHg
- 比重(密度) :
- 1.694±0.06 g/cm3(Predicted)
- 闪点 :
- >230 °F
- 貯蔵温度 :
- Keep in dark place,Sealed in dry,Room Temperature
- 外見 :
- powder to crystal
- 酸解離定数(Pka):
- 1.52±0.10(Predicted)
- 色:
- White to Light yellow to Dark green
- InChI:
- InChI=1S/C6H5BrFN/c7-5-2-1-4(8)3-6(5)9/h1-3H,9H2
- InChIKey:
- FWTXFEKVHSFTDQ-UHFFFAOYSA-N
- SMILES:
- C1(N)=CC(F)=CC=C1Br
- CAS データベース:
- 1003-99-2(CAS DataBase Reference)
2-ブロモ-5-フルオロアニリン 価格
もっと(19)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01APOPC7394 |
2-ブロモ-5-フルオロアニリン
2-Bromo-5-fluoroaniline |
1003-99-2 |
25g |
￥4800 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01APOPC7394 |
2-ブロモ-5-フルオロアニリン
2-Bromo-5-fluoroaniline |
1003-99-2 |
100g |
￥22600 |
2023-06-01 |
購入 |
|
東京化成工業
|
B2163 |
2-ブロモ-5-フルオロアニリン >98.0%(GC)
2-Bromo-5-fluoroaniline
>98.0%(GC) |
1003-99-2 |
5g |
￥6100 |
2024-03-01 |
購入 |
|
東京化成工業
|
B2163 |
2-ブロモ-5-フルオロアニリン >98.0%(GC)
2-Bromo-5-fluoroaniline
>98.0%(GC) |
1003-99-2 |
25g |
￥18500 |
2024-03-01 |
購入 |
|
関東化学株式会社(KANTO)
|
04715-52 |
２‐ブロモ‐５‐フルオロアニリン >97.0%(HLC)
2‐Bromo‐5‐fluoroaniline >97.0%(HLC) |
1003-99-2 |
5g |
￥3700 |
2024-07-01 |
購入 |
2-ブロモ-5-フルオロアニリン 化学特性,用途語,生産方法
外観
微褐白色～褐黄色、結晶～結晶性粉末
説明
2-bromo-5-fluoroaniline: a intermediate of antitumor drug.
2-bromo-5-fluoroaniline is the intermediate of antitumor drug Phortress, phortress is the benzothiazoles CYP1A1 antitumor drugs targeting by Univ Nottingham UK invention, solution becomes lipophilic compound 5F2O3(10 in the sensitive cells but Phortress enters), the latter is as potential aromatic hydrocarbon receptor (AhR) agonist, induce CYP1A1 to express, CYP1A1 metabolism through expressing produces and has high electrophilic active substance again, finally causes DNA damage and apoptosis. The method that, at present, synthetic 2-bromo-5-fluoronitrobenzene prepares 2-bromo-5-fluoroaniline is divided into two large classes:
The one: adopt a chemical reduction method, utilizing the chemical reducing agent reductase 2-bromo-5-fluoronitrobenzenes such as protochloride glass putty, iron powder, vat powder, hydrazine, and sodium borohydride (potassium), which is 2-bromo-5-fluoroaniline.
The 2nd: adopt hydro-reduction. What we do more often both at home and abroad at present is chloride or the catalytic hydrogenation of fluorine-containing arylamine, and the brominated less report of arylamine hydrogenation mainly is easily by hydrogenolysis because of bromine.
化学的特性
Yellow to brown crystalline powder
使用
2-Bromo-5-fluoroaniline may be used to synthesize:
- orthobromothiobenzanilide of 5-fluoronitrobenzothiazole
- 2-bromo-5-fluorobenzo[14C]nitrile
- [3-14C]-5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
- 2-bromo-5-fluoro-phenyl)-(2-methoxy-6-pentadecyl-benzyl)amine
2-ブロモ-5-フルオロアニリン 上流と下流の製品情報
原材料
準備製品
2-ブロモ-5-フルオロアニリン 生産企業
Global( 366)Suppliers
2-ブロモ-5-フルオロアニリン スペクトルデータ(IR、MS)
1003-99-2(2-ブロモ-5-フルオロアニリン)キーワード:
- 1003-99-2
- 2-BROMO-5-FLUOROBENZENAMINE
- 2-BROMO-5-FLUOROANILINE
- 2-Bromo-5-fluoroaniline 98%
- 2-Bromo-5-fluoroaniline98%
- 2-Bromo-5-fluoroaniline,99%
- 2-Bromo-5-fluoroanil
- BenzenaMine, 2-broMo-5-fluoro-
- 2-BroMo-5-fluoroaniline, 99% 25GR
- 2-broMo-5-fluoroaniline, 2-broMo-5-fluoro-phenylaMine, 2-broMo-5-fluorobenzeneaMine, 2-broMo-5-fluorobenzenaMine, 2-broMo-5-fluoro aniline, 2-broMo-5-fluoro-aniline, 2-BroM-5-fluor-anilin
- 2-Bromo-5-fluoroaniline ISO 9001：2015 REACH
- 2-Bromo-5-fluoroaniline >
- 2-Bromo-5-fluoro-phenylamine
- 13-Cyanophenyl&isocyanate
- Nitazoxanide Impurity 4（SU 3327）
- Vandetanib Impurity 3
- 2-ブロモ-5-フルオロアニリン
- 2‐ブロモ‐5‐フルオロアニリン