(R)-6-[4-[(4-エチルピペラジン-1-イル)メチル]フェニル]-N-(1-フェニルエチル)-7H-ピロロ[2,3-d]ピリミジン-4-アミン

(R)-6-[4-[(4-エチルピペラジン-1-イル)メチル]フェニル]-N-(1-フェニルエチル)-7H-ピロロ[2,3-d]ピリミジン-4-アミン 価格 もっと(4)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01TOC5318	AEE 788	497839-62-0	10mg	￥91000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TOC5318	AEE 788	497839-62-0	50mg	￥377000	2024-03-01	購入
Sigma-Aldrich Japan	SML1400	≥98% (HPLC) AEE788 ≥98% (HPLC)	497839-62-0	5mg	￥22000	2021-03-23	購入
Sigma-Aldrich Japan	SML1400	≥98% (HPLC) AEE788 ≥98% (HPLC)	497839-62-0	25mg	￥70240	2021-03-23	購入

(R)-6-[4-[(4-エチルピペラジン-1-イル)メチル]フェニル]-N-(1-フェニルエチル)-7H-ピロロ[2,3-d]ピリミジン-4-アミン 化学特性,用途語,生産方法

説明

AEE788 is an inhibitor of both epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) receptor tyrosine kinase family members. It can inhibit EGFR and VEGFR tyrosine kinases with IC₅₀ values of 2, 6, 77, and 59 nM for EGFR, ErbB2, KDR, and FLT1, respectively. AEE788 demonstrates antiproliferative activity against a range of EGFR and ErbB2-overexpressing cell lines and can inhibit the proliferation of EGF- and VEGF-stimulated human umbilical vein endothelial cells. It also has been shown to have antitumor and anti-angiogenic activity in numerous animal models of cancer.

使用

AEE788 is a novel multitargeted human epidermal receptor (HER) 1/2 and vascular endothelial growth factor receptor (VEGFR) 1/2 receptor family tyrosine kinases inhibitor with IC50 of 2, 6, 77, 59 nM for EGFR, ErbB2, KDR, and Flt-1.

(R)-6-[4-[(4-エチルピペラジン-1-イル)メチル]フェニル]-N-(1-フェニルエチル)-7H-ピロロ[2,3-d]ピリミジン-4-アミン 上流と下流の製品情報

原材料

準備製品

(R)-6-[4-[(4-エチルピペラジン-1-イル)メチル]フェニル]-N-(1-フェニルエチル)-7H-ピロロ[2,3-d]ピリミジン-4-アミン 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29825	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	24330	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9602	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10522	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58

497839-62-0((R)-6-[4-[(4-エチルピペラジン-1-イル)メチル]フェニル]-N-(1-フェニルエチル)-7H-ピロロ[2,3-d]ピリミジン-4-アミン)キーワード:

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• 497839-62-0
• AEE788 (NVP-AEE788);AEE-788;AEE 788;NVP-AEE 788
• (R)-6-(4-((4-Ethylpiperazin-1-yl)methyl)phenyl)-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4
• AEE788
• (R)-6-(4-((4-Ethylpiperazin-1-yl)methyl)phenyl)-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• 7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, 6-[4-[(4-ethyl-1-piperazinyl)Methyl]phenyl]-N-[(1R)-1-phenylethyl]-
• [6-[4-(4-ethyl-piperazine-1-ylMethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrinidinpyriMidin-4-yl]-((R)-1-phenyl-ethyl)-aMine
• AEE 788AEE-788
• [6-[4-[(4-Ethylpiperazin-1-yl)Methyl]phenyl]-7H-pyrrolo[2,3-d]pyriMidin -4-yl]-((R)-1-phenylethyl)aMine
• AEE788 (NVP-AEE788)
• NVP-AEE788
• 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine AEE 788
• AEE788 USP/EP/BP
• CS-375
• 6-(4-((4-ethyl-1-piperazinyl)methyl)phenyl)-N-((1R)-1-phenylethyl)-1H-Pyrrolo(2,3-D)pyrimidin-4-amine
• 6-(4-((4-ethylpiperazin-1-yl)methyl)phenyl) -N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• (R)-6-[4-[(4-エチルピペラジン-1-イル)メチル]フェニル]-N-(1-フェニルエチル)-7H-ピロロ[2,3-d]ピリミジン-4-アミン
• 6-{4-[(4-エチルピペラジン-1-イル)メチル]フェニル}-N-[(1R)-1-フェニルエチル]-7H-ピロロ[2,3-d]ピリミジン-4-アミン
• N-[(R)-1-フェニルエチル]-6-[4-[(4-エチル-1-ピペラジニル)メチル]フェニル]-7H-ピロロ[2,3-d]ピリミジン-4-アミン
• AEE-788