アフレセルチブ塩酸塩 化学特性,用途語,生産方法
効能
抗悪性腫瘍薬, AKTセリン/スレオニンキナーゼ阻害薬
使用
Afuresertib is a selective, orally bioavailable inhibitor of Akt1, 2, and 3 with Ki values of 0.08, 2, and 2.6 nM, respectively. It preferentially inhibits the proliferation of human cancer cell lines with Akt pathway activation and various cell lines derived from hematologic malignancies with minimal effect on glucose homeostasis. Afuresertib demonstrates activity against multiple myeloma in both preclinical and clinical models.[Cayman Chemical]
アフレセルチブ塩酸塩 上流と下流の製品情報
原材料
準備製品