NSC 55712
NSC 55712 物理性質
- 融点 :
- 210℃ (Decomposition)
- 貯蔵温度 :
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- 溶解性:
- DMSO:62.5(Max Conc. mg/mL);240.02(Max Conc. mM)
- 外見 :
- A crystalline solid
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
NSC 55712 価格
もっと(3)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQJ-4939 |
Tpt-260 dihydrochloride |
2076-91-7 |
100mg |
￥895000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01FLC468355 |
TPT-260 2HCL |
2076-91-7 |
250mg |
￥226900 |
2021-03-23 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01FLC468355 |
TPT-260 2HCL |
2076-91-7 |
1g |
￥566900 |
2021-03-23 |
購入 |
NSC 55712 化学特性,用途語,生産方法
使用
Retromers are multiprotein complexes responsible for trafficking cargo out of endosomes. This is an important function that, in the case of amyloid-precursor protein (APP), is neuroprotective by preventing APP from being cleaved into Alzheimer’s disease-inducing fragments via the endosome. TPT-260 is a thiophene thiourea derivative that acts as a chaperone to stabilize the retromer complex against thermal denaturation (Kd = ~5 μM). In cultured hippocampal neurons, TPT-260 dose-dependently increases the level of retromer proteins, redirects APP from the endosome, and reduces the formation of pathogenic APP.[Cayman Chemical]
NSC 55712 上流と下流の製品情報
原材料
準備製品
NSC 55712 生産企業
Global( 56)Suppliers
- 2076-91-7
- NSC 55712
- TPT-260 (Dihydrochloride)
- THIOPHENE-2,5-DIYLBIS(METHYLENE) DICARBAMIMIDOTHIOATE.2HCL
- TPT-260 (Dihydrochloride), NSC55712
- TPT-260 2HCl
- Carbamimidothioic acid 2,5-thiophenediylbis(methylene) ester dihydrochloride
- TPT-260 , NSC55712
- NSC 55712 Carbamimidothioic acid 2,5-thiophenediylbis(methylene) ester dihydrochloride
- TPT-260 Dihydrochloride, >=98%
- Thiophene-2,5-diylbis(methylene) dicarbamimidothioate dihydrochloride
- NSC55712 Dihydrochloride
- TPT-260 2HCl(NSC55712)
- R 55
- TPT-260 (hydrochloride)
- thiene-2,5-diyldimethanediyl dicarbamimidothioate
- Carbamimidothioic acid,C,C'-[2,5-thiophenediylbis(methylene)] ester, hydrochloride (1:2)
- NSC55712; TPT260 DIHYDROCHLORIDE; TPT 260 DIHYDROCHLORIDE; TPU-260 DIHYDROCHLORIDE;NSC-55712;NSC 55712
- TPU-260 Dihydrochloride
- [({5-[(carbamimidoylsulfanyl)methyl]thiophen-2-yl}methyl)sulfanyl]methanimidamide dihydrochloride
- TPT-260 2HCl (R55)
- TPT 260 Dihydrochloride,Inhibitor,inhibit,TPU 260,TPU260,TPT260 Dihydrochloride,NSC 55712,TPU-260,NSC-55712