(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate

 化学構造式
1714114-25-6
CAS番号.
1714114-25-6
化学名:
别名:
英語名:
(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate
英語别名:
D-Alanine, N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester;(S)-Isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate (sofosbuvir Impurity)
CBNumber:
CB02715788
化学式:
C18H17F5NO5P
分子量:
453.3
MOL File:
1714114-25-6.mol

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate 物理性質

沸点 :
442.6±55.0 °C(Predicted)
比重(密度) :
1.405±0.06 g/cm3(Predicted)
酸解離定数(Pka):
-3.81±0.70(Predicted)

安全性情報

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate 化学特性,用途語,生産方法

使用

N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-D-alanine 1-Methylethyl Ester is an impurity of PSI-7977 (P839640); a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate 上流と下流の製品情報

原材料

準備製品


(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate 生産企業

Global( 10)Suppliers
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  • 1714114-25-6
  • D-Alanine, N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester
  • (S)-Isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate (sofosbuvir Impurity)
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