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Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2

化学構造式
689284-12-6
CAS番号.
689284-12-6
化学名:
别名:
英語名:
Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2
英語别名:
TAPI-2 acetate salt;Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2;N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-t-butyl-glycine-L-alanine 2-aminoethyl amide;N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide;L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-
CBNumber:
CB02750664
化学式:
C19H37N5O5
分子量:
415.53
MOL File:
689284-12-6.mol
MSDS File:
SDS

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 物理性質

貯蔵温度 :
-20°C
外見 :
凍結乾燥固体
色:
ホワイトからオフホワイト

安全性情報

WGK Germany  3

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 価格 もっと(1)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
Sigma-Aldrich Japan SML0420 ≥98% (HPLC)
TAPI-2 acetate salt ≥98% (HPLC)		 689284-12-6 1mg ￥76100 2024-03-01 購入

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 化学特性,用途語,生産方法

使用

TAPI 2 is a matrix metalloprotease (MMP) inhibitor, which inhibits merpin α and β homo-oligomers.

Biochem/physiol Actions

TAPI-2 is a potent inhibitor matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase). It blocks the shedding of several cell surface proteins such as β-amyloid precursor protein, inhibits TNF-α release as well as a diverse variety of membrane-anchored cytokines, cell adhesion molecules, receptors, ligands. TAPI-2 is considered a fairly broad metalloproteinase inhibitor, but it much more selective for TACE than GM6001.

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 上流と下流の製品情報

原材料

準備製品

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 生産企業

Global( 9)Suppliers
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Sigma-Aldrich 021-61415566 800-8193336
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3477467573@qq.com China 8617 58
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Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581
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  • 689284-12-6
  • N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-t-butyl-glycine-L-alanine 2-aminoethyl amide
  • TAPI-2 acetate salt
  • Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2
  • N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide
  • L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-
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