Anti-Myocyte nuclear factor 化学特性,用途語,生産方法
使用
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project
(www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these
protocols and other useful information about Prestige Antibodies and the HPA, visit .
一般的な説明
Forkhead box protein K1 (FOXK1) is expressed in tissues of the brain, heart and lungs during the developmental stages. The gene encoding FOXK1 is located on chromosome 7p22.
Biochem/physiol Actions
Forkhead box protein K1 (FOXK1) interacts with dishevelled protein (DVL) and transports it to the nucleus. This is important for the progress and positive regulation of the Wnt signaling pathway. Knockdown of FOXK1 leads to diminished cell proliferation rates. FOXK1 binds and regulates genes that are related to cell cycle like DHFR (Dihydrofolate reductase) and TYMS (Thymidylate synthase). It has been shown that its expression is heightened in colorectal cancers.
Anti-Myocyte nuclear factor 上流と下流の製品情報
原材料
準備製品