抗CIT抗体 ウサギ宿主抗体 化学特性,用途語,生産方法
使用
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project
(www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these
protocols and other useful information about Prestige Antibodies and the HPA, visit .
一般的な説明
The gene CIT (citron Rho-interacting kinase) is mapped to human chromosome 12q24. The protein is present at the cleavage furrow and the midbody in the nucleus. CIT contains an amino-terminal kinase domain, an internal coiled-coil domain and a carboxyl-terminal region consisting of a zinc finger, a pleckstrin homology domain, a citron homology domain, a putative SH3 (src Homology-3) binding domain and a PDZ (discs-large homologous regions)-targeting motif.
Biochem/physiol Actions
CIT (citron Rho-interacting kinase) is crucial for cytokinesis. It is required for stabilization of the midbody structure when the cell moves to abscission through active RhoA (ras homolog gene family, member A) and actin binding protein, anillin. It is also linked with human immunodeficiency virus type 1 (HIV-1) virion production.
抗CIT抗体 ウサギ宿主抗体 上流と下流の製品情報
原材料
準備製品