ANTI-TUBERIN

ANTI-TUBERIN 価格 もっと(4)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
Sigma-Aldrich Japan	SAB4503037	affinity isolated antibody Anti-TSC2 antibody produced in rabbit affinity isolated antibody		100μG	￥97700	2024-03-01	購入
Sigma-Aldrich Japan	PRS3507	affinity isolated antibody, buffered aqueous solution Anti-TSC2 (ab1) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution		100μG	￥92400	2024-03-01	購入
Sigma-Aldrich Japan	HPA030409	Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution Anti-TSC2 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution		100μL	￥79600	2024-03-01	購入
Sigma-Aldrich Japan	HPA030409	Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution Anti-TSC2 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution		25μL	￥33900	2023-06-01	購入

ANTI-TUBERIN 化学特性,用途語,生産方法

使用

Anti-Tuberin (VV-18) antibody produced in rabbit may be used in immunoblotting and immunoprecipitation.

一般的な説明

Tuberin is encoded by the gene tuberous sclerosis complex subunit 2 (TSC2) which is mapped on the human chromosome at 16p13.3. Tuberin gene is widely expressed in mammalian cell lines and tissues. It co-localizes with hamartin in most tissues and cell types. Tuberin is found in cytosolic, microsomal, cytoskeletal, and vesicular fractions and in certain cells. It is also localized to the nucleus.

Biochem/physiol Actions

Tuberin along with hamartin plays a role in the regulation of cell cycle, cell growth and cell differentiation. It also plays a role in cell adhesion and vesicular trafficking. Tuberin has a guanidine triphosphatase (GTPase) activating protein homology (GAP) domain thatis involved in the regulation of the small GTPase Ras homolog enriched in brain (RHEB) both in vitro and in vivo. Tuberin along with hamartin forms a functional cytoplasmic complex that inhibits growth by inhibiting phosphorylation of S6 kinase 1 (S6K1) and 4E binding protein 1 (4EBP1), probably through their upstream modulator mammalian target of rapamycin (mTOR). Mutations in the tuberous sclerosis complex subunit 2 (TSC2) gene are associated with tuberous sclerosis (TSC), an autosomal dominant hereditary disease characterized by mental retardation, seizures and benign tumors (hamartomas) in multiple organs including the kidney, brain, heart and skin. Tuberin and hamartin are involved in the phosphoinositide 3-kinase/ Akt signal transduction pathway.

ANTI-TUBERIN 上流と下流の製品情報

原材料

準備製品

ANTI-TUBERIN 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Suzhou Ruinuode Biotechnology Co., Ltd.	--	2090855807@qq.com	CHINA	6063	58
Shanghai Beinuo Biotechnology Co., Ltd.	--	beinuobio@163.com	CHINA	6580	58
Beijing Zhijie Fangyuan Technology Co., Ltd.	--	15810200961@163.com	CHINA	6984	58
BEIJING BIOSYNTHESIS BIOTECHNOLOGY CO., LTD.	--	sales@bioss.com.cn	CHINA	6717	58
Shanghai Hao Biological Technology Co., Ltd.	--	market@xlswkj.com	CHINA	6805	58
Beijing Bi Orange Blue Biotechnology Co., Ltd.	--	bo49855987@163.com	CHINA	6827	58
Nanjing Sai Ruirui Biotechnology Co., Ltd.	--	sales@shrbio.com	CHINA	6873	58
Shanghai Ziqi Biological Technology Co., Ltd.	--	2453006496@qq.com	CHINA	6192	58
Riedel-de Haen AG	--		United States	6825	87
SIGMA-RBI	--		Switzerland	6913	91

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• ANTI-TUBERIN
• ANTI-TUBERIN (VV-18)
• Anti-ACTA3
• Anti-ACTL3
• Anti-ACTSG
• Anti-LAM
• Anti-TSC2 antibody produced in rabbit
• Anti-TSC4
• Anti-tuberous sclerosis 2
• Anti-Hamartin/TSC1 (Isoform 1) antibody produced in goat
• Anti-HGNC:12362
• Anti-KIAA0243
• Anti-TSC2 (ab1) antibody produced in rabbit
• Anti-TSC2 (ab2) antibody produced in rabbit
• Anti-Tuberin (VV-18) antibody produced in rabbit