KEA1-97

 化学構造式
2138882-71-8
CAS番号.
2138882-71-8
化学名:
别名:
英語名:
KEA1-97
英語别名:
KEA1-97;KEA1-97 >=98% (HPLC);4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)-;Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197
CBNumber:
CB04668109
化学式:
C15H9Cl2FN4
分子量:
335.16
MOL File:
2138882-71-8.mol

KEA1-97 物理性質

沸点 :
530.3±52.0 °C(Predicted)
比重(密度) :
1.466±0.06 g/cm3(Predicted)
貯蔵温度 :
4°C, protect from light
溶解性:
DMSO : 100 mg/mL (298.36 mM; Need ultrasonic)
酸解離定数(Pka):
0.57±0.10(Predicted)

安全性情報

KEA1-97 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

KEA1-97 化学特性,用途語,生産方法

説明

KEA1-97 is a Thioredoxin-Caspase 3 interaction disruptor. It was found to target lysine 72 of thioredoxin, inhibiting its interactions with caspase 3 and inducing apoptosis without affecting other thioredoxin activity. KEA1-97 induced apoptosis in breast cancer cells and treatment of immune-deficient SCID mice at 5 mg/kg ip impaired breast tumor xenograft growth.

KEA1-97 上流と下流の製品情報

原材料

準備製品


KEA1-97 生産企業

Global( 27)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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  スペクトルデータ(1HNMR)



  • 2138882-71-8
  • KEA1-97
  • 1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)-
  • KEA1-97 >=98% (HPLC)
  • 4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine
  • Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197
  • 4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine
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