Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-
Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)- 物理性質
- 沸点 :
- 621.7±55.0 °C(Predicted)
- 比重(密度) :
- 1.54±0.1 g/cm3(Predicted)
- 酸解離定数(Pka):
- 13.80±0.40(Predicted)
安全性情報
Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)- 価格
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Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)- 化学特性,用途語,生産方法
使用
10α-Hydroxy Nicergoline is an impurity of Nicergoline (N394550) which is a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia. Nicergoline has shown to protect cultured neurons against β-amyloid toxicity. Nicergoline protects against neuronal cell death induced by activated microglia and astrocytes through the inhibition of inflammatory mediators and the upregulation of neurotrophic factors by glial cells. Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.
Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)- 上流と下流の製品情報
原材料
準備製品
Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)- 生産企業
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- 57935-66-7
- Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-
- Ergoline-8-methanol Indolo[4,3-fg]quinoline Derivative
- 10α-Hydroxy Nicergoline
- NicergolineImpurity2
- 10-Hydroxynicergoline
- Nicergoline EP Impurity 7