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GLY-ARG-GLY-ASP-SER-PRO-LYS

化学構造式
111119-28-9
CAS番号.
111119-28-9
化学名:
别名:
英語名:
GLY-ARG-GLY-ASP-SER-PRO-LYS
英語别名:
GRGDSPK;EMD 56574;GRGDSPK (EMD 56574);GLY-ARG-GLY-ASP-SER-PRO-LYS;H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH;GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE;GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE;Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC);glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine
CBNumber:
CB1123649
化学式:
C28H49N11O11
分子量:
715.76
MOL File:
111119-28-9.mol
MSDS File:
SDS

GLY-ARG-GLY-ASP-SER-PRO-LYS 物理性質

比重(密度) :
1.59±0.1 g/cm3(Predicted)
貯蔵温度 :
-20°C
酸解離定数(Pka):
3.60±0.21(Predicted)
外見 :
Solid
色:
White to off-white

安全性情報

WGK Germany  3

GLY-ARG-GLY-ASP-SER-PRO-LYS 価格 もっと(3)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01BCS4011392
H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH, Trifluoroacetate 		111119-28-9 1mg ￥32000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01BCS4011392
H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH, Trifluoroacetate 		111119-28-9 5mg ￥92000 2020-09-21 購入
Sigma-Aldrich Japan G1269 ≥97% (HPLC)
Gly-Arg-Gly-Asp-Ser-Pro-Lys ≥97% (HPLC)		 111119-28-9 1mg ￥57200 2024-03-01 購入

GLY-ARG-GLY-ASP-SER-PRO-LYS 化学特性,用途語,生産方法

使用

Gly-Arg-Gly-Asp-Ser-Pro-Lys (RGD peptide) has been used-
  • as a blocking peptide to inhibit integrin-fibronectin binding
  • in adhesion assay performed on porcine trophectoderm to study the influence of TGFβ (transforming growth factor) on cell adhesion
  • for incubation of MC3T3-E1 osteoblast cells to determine its effect on cell adhesion measured by AFM (atomic force microscopy)
  • for the preparation of RGD.Flt23k.NR nanoparticles
  • to determine the involvement of RGD-integrin bonding in cell adhesion process

一般的な説明

Gly-Arg-Gly-Asp-Ser-Pro-Lys is a RGD peptide. Naturally occurring RGD peptides, present in the ECM (extracellalar matrix) proteins, are involved in facilitating integrin-mediated cell adhesion to matrix proteins. RGD peptide is present as repeats in cell-adhesion protein, such as fibronectin and vitronectin. This tripeptide is recognized by cells by specific integrins (e.g. β1 , β3 , and β5 subunits), present on the cell surface and associated with the actin filament via the FA (focal adhesion)-complex.

Biochem/physiol Actions

Fibronectin analog that binds to integrins.

GLY-ARG-GLY-ASP-SER-PRO-LYS 上流と下流の製品情報

原材料

準備製品

GLY-ARG-GLY-ASP-SER-PRO-LYS 生産企業

Global( 74)Suppliers
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Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
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 anna@api-made.com China 2944 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52927 58

111119-28-9()キーワード:

RGDSペプチド H-ARG-GLY-ASP-OH
  • 111119-28-9
  • H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH
  • GRGDSPK
  • GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE
  • GLY-ARG-GLY-ASP-SER-PRO-LYS
  • GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE
  • glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine
  • EMD 56574
  • L-Lysine, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-
  • Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC)
  • Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine
  • GRGDSPK (EMD 56574)
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