ゴルジシドA

ゴルジシドA 価格 もっと(4)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01TOC3584	Golgicide A	1139889-93-2	10mg	￥78000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TOC3584	Golgicide A	1139889-93-2	50mg	￥323000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TRCG766500	ゴルジシドA Golgicide A	1139889-93-2	25mg	￥53900	2023-06-01	購入
富士フイルム和光純薬株式会社(wako)	W01TRCG766500	ゴルジシドA Golgicide A	1139889-93-2	250mg	￥421600	2023-06-01	購入

ゴルジシドA 化学特性,用途語,生産方法

一般的な説明

A cell-permeable quinoline compound that selectively targets ArfGEF GBF1, but not BIG1/2, and attenuates GBF1-mediated cellular vesicle traffickings in a reversible manner. Phenotypic comparisons in Vero (African Green Monkey Kidney epithelial) cultures reveal that selective blockage of GBF1 function by GCA (10 μM) or by FGB1-E794K dominant-inactive expression affects medial- and cis-Golgi similarly to that seen with BFA (Cat. No. 203729), however, the non-GBF1-specific BFA (10 μg/ml or 35.6 μM) causes additional GBF1-independent morphologic effects on TGN, notably the rapid dispersal of Golgi-associated coat proteins AP-1 and GGA3, which are not seen with GCA treatment. Endocytic/retrograde transport studies using GCA establishes that GBF1 function is not required for the transport of bacterial toxins to the endosomes, however the retrograde transport of StxB (shiga toxin B subunit) from endosomes to TGN and Golgi is GBF1-dependent (100% inhibition of StxB sulfation at 10 μM), accounting for GCA′s (10 μM) ability to completely prevent Vera cells from Stx-induced (up to 100 ng/ml) inhibition of cellular protein synthesis.

ゴルジシドA 上流と下流の製品情報

原材料

準備製品

ゴルジシドA 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32836	60
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30250	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	23699	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69

1139889-93-2(ゴルジシドA)キーワード:

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• 1139889-93-2
• 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
• Golgicide A
• 3H-Cyclopenta[c]quinoline, 6,8-difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-, (3aR,9bS)-rel-
• Golgicide A - CAS 1139889-93-2 - Calbiochem
• 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline USP/EP/BP
• rel-(3aR,9bS)-6,8-Difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
• Golgicide A (GCA)
• ゴルジシドA
• 4-(3-ピリジニル)-6,8-ジフルオロ-3aα,4,5,9bα-テトラヒドロ-3H-シクロペンタ[c]キノリン
• ゴルギシドA
• 3-[(3aR,9bS)-6,8-ジフルオロ-3H,3aH,4H,5H,9bH-シクロペンタ[c]キノリン-4-イル]ピリジン