MDA 19

 化学構造式
1048973-47-2
CAS番号.
1048973-47-2
化学名:
别名:
英語名:
MDA 19
英語别名:
MDA 19;MDA19; MDA-19;N'-(1-Hexyl-2-oxoindolin-3-ylidene)benzohydrazide;(Z)-N'-(1-hexyl-2-oxoindolin-3-ylidene)benzohydrazide;N-[(Z)-(1-Hexyl-2-oxo-indolin-3-ylidene)aMino]benzaMide;N'-[(3Z)-1-Hexyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazide;Benzoic acid (2Z)-2-(1-hexyl-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide;MDA 19 (Z)-N'-(1-hexyl-2-oxoindolin-3-ylidene)benzohydrazide
CBNumber:
CB12535682
化学式:
C21H23N3O2
分子量:
349.43
MOL File:
1048973-47-2.mol

MDA 19 物理性質

比重(密度) :
1.16±0.1 g/cm3 (20 ºC 760 Torr)
貯蔵温度 :
Store at -20°C
溶解性:
DMF: 20 mg/ml; DMSO: 10 mg/ml; Ethanol: 3 mg/ml; Methanol: 1 mg/ml
外見 :
A crystalline solid
酸解離定数(Pka):
10.45±0.20(Predicted)
色:
Light yellow to yellow

安全性情報

MDA 19 化学特性,用途語,生産方法

使用

MDA 19 is a selective agonist of the human peripheral cannabinoid (CB2) receptor. A cell-based functional assay showed MDA is an inverse agonist of the CB2 receptor in rat. Acts as an inverse agonist at the rat CB2 receptor. Reported Ki values are 16.3 and 1130 nM for human CB2 and CB1 receptor respectively. MDA19 was effective in attenuating tactile allodynia in neuropathic rats. MDA19 thus has potential for alleviating neuropathic pain without producing adverse effects in the central nervous system.Synthetic Cannabinoids

MDA 19 上流と下流の製品情報

原材料

準備製品

1048973-47-2()キーワード:


  • 1048973-47-2
  • (Z)-N'-(1-hexyl-2-oxoindolin-3-ylidene)benzohydrazide
  • N'-(1-Hexyl-2-oxoindolin-3-ylidene)benzohydrazide
  • MDA 19 (Z)-N'-(1-hexyl-2-oxoindolin-3-ylidene)benzohydrazide
  • MDA 19
  • N'-[(3Z)-1-Hexyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazide
  • Benzoic acid (2Z)-2-(1-hexyl-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide
  • N-[(Z)-(1-Hexyl-2-oxo-indolin-3-ylidene)aMino]benzaMide
  • MDA19; MDA-19
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