Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester

1246213-45-5

CAS番号.: 1246213-45-5

化学名:

别名:

英語名:: Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester

英語别名:: Ivacaftor Methylcarbonate;N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide;2,4-di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl methyl carbonate;Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester

CBNumber:: CB12657777

化学式:: C26H30N2O5

分子量:: 450.53

MOL File:: 1246213-45-5.mol

物理性質

安全性情報

用途語

生産企業 20

Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester 物理性質

沸点 :: 583℃

比重(密度) :: 1.198

闪点 :: 306℃

溶解性:: アセトン、ジクロロメタン、メタノール

外見 :: 個体

酸解離定数(Pka):: 11.60±0.70(Predicted)

色:: 泡立つ

安全性情報

Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester 化学特性,用途語,生産方法

使用

N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide is an intermediate in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603). Ivacaftor (4-tertbutyl-d9) (Major) is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis.

Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester 上流と下流の製品情報

原材料

5-amino-2,4-di-tert-butylphenyl methyl carbonate 1,4-ジヒドロ-4-オキソキノリン-3-カルボン酸

準備製品

Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester 生産企業

Global( 20)Suppliers

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Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Shijiazhuang Dingmin Pharmaceutical Sciences Co., Ltd.	+86-0311-67591193 +8613931880626	sales02@dingminpharma.com	China	252	58
Shanghai YuLue Chemical Co., Ltd.	021-60345187 13671753212	lzz841106@aliyun.com	China	10274	55
Jinan Putubio Tech Co., Ltd.	+86 (531) 8099-2215	putubio@outlook.com	China	1261	55
Jinan elephant international trading co., LTD		13006575422@163.com	China	6355	58
Dezhou LonWel Pharmaceutical Technology Co., Ltd.	13761310616	39324283@qq.com	China	1991	58
Jinan Yaoyan Pharmaceutical Co., Ltd.		jnyaoyan@163.com	China	3069	58
Shanghai Moss Medicine Technology Co., Ltd.	+86-188369842 +86-15618151133	188369842@qq.com	China	1944	58