Neurogenic locus notch homolog protein 2 precursor 化学特性,用途語,生産方法
一般的な説明
Anti-NOTCH2 (Cleaved-Val
1697) antibody detects endogenous levels of fragment of activated NOTCH2 (Cleaved-Val
1697) protein.
Biochem/physiol Actions
The NOTCH2 gene is known to be involved in the proliferation, cell cycle progression and colony formation of cancer cells. Upregulation of the gene is observed in hepatocellular carcinoma and salivary adenoid cystic carcinoma. Deletion of NOTCH2 increases the sensitivity of the cancer cells to chemotherapeutic agents such as 5-fluorouracil. NOTCH2 plays an important role in the regulation of liver development.
Neurogenic locus notch homolog protein 2 precursor 上流と下流の製品情報
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