ヘキサペプチド-11 化学特性,用途語,生産方法
定義
本品は、アラニン(*)、フェニルアラニン(*)、プロリン(*)及びバリン(*)残基を含む合成ペプチドである。参照表示名称：アラニン, フェニルアラニン, プロリン, バリン
化粧品の成分用途
皮膚コンディショニング剤
説明
Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts.
使用
Hexapeptide-11 reduces the appearance of fine lines and wrinkles, making this an excellent addition to all kinds of skin care and anti-aging products. It has a unique set of amino acids that help to manipulate collagen levels and boost elasticity in the skin.
Physiological effects
Exposure of fibroblasts to Hexapeptide-11 promoted dose and time-dependent activation of proteasome, autophagy, chaperones and antioxidant responses related genes. Moreover, it promoted increased nuclear accumulation of Nrf2; higher expression levels of proteasomal protein subunits and increased proteasome peptidase activities. In line with these findings we noted that Hexapeptide-11 conferred significant protection in fibroblasts against oxidative-stress-mediated premature cellular senescence, while at in vivo skin deformation assays in human subjects it improved skin elasticity.
ヘキサペプチド-11 上流と下流の製品情報
原材料
準備製品