SCHIZOZYGINE 化学特性,用途語,生産方法
説明
The major alkaloid obtained from the bark and roots of Schizozygia caffaeoides (Boj.) Baill. The base has [α]
23D + 15.5° (c 1.0, CHC1
3) and gives an ultraviolet spectrum having absorption maxima at 269 and 313 mil. The alkaloid possesses both antipyretic and broncholytic properties. When hydrogenated in AcOH in the presence of Pt0
2 it yields the dihydro derivative, m.p. 190-1°C;[α]
24D + 29.4° (c 1.0, CHCI
3). Hydrogenation with LiAIH
4, however, gives deoxoschizozygine, m.p. 213-233°C (dec.); [α]
26D + 82.9° (c 1.0, CHCI
3). The two reduction processes are protected by patents.
参考文献
Renner, Kernweisz., Experientia, 19,244 (1963)
Structure:
Renner., Lloydia, 27,406 (1964)
Renner., Swiss Patent 451,182,15 May 1968
Renner., Swiss Patent 451,183,15 May 1968
SCHIZOZYGINE 上流と下流の製品情報
原材料
準備製品