Des-3-(Furan-3-yl) 3-(Furan-2-yl) 10α-Hydroxy Nalfurafine

 化学構造式
2133305-36-7
CAS番号.
2133305-36-7
化学名:
别名:
英語名:
Des-3-(Furan-3-yl) 3-(Furan-2-yl) 10α-Hydroxy Nalfurafine
英語别名:
2-Propenamide, N-[(5α,6β,10α)-17-(cyclopropylmethyl)-4,5-epoxy-3,10,14-trihydroxymorphinan-6-yl]-3-(2-furanyl)-N-methyl-, (2E)-;(E)-N-((4R,4aS,7R,7aR,12bS,13S)-3-(Cyclopropylmethyl)-4a,9,13-trihydroxy-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl)-3-(furan-2-yl)-N-methylacrylamide
CBNumber:
CB16080975
化学式:
C28H32N2O6
分子量:
492.56
MOL File:
2133305-36-7.mol

Des-3-(Furan-3-yl) 3-(Furan-2-yl) 10α-Hydroxy Nalfurafine 物理性質

沸点 :
742.6±60.0 °C(Predicted)
比重(密度) :
1.47±0.1 g/cm3(Predicted)
酸解離定数(Pka):
9.19±0.70(Predicted)

安全性情報

Des-3-(Furan-3-yl) 3-(Furan-2-yl) 10α-Hydroxy Nalfurafine 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

Des-3-(Furan-3-yl) 3-(Furan-2-yl) 10α-Hydroxy Nalfurafine 化学特性,用途語,生産方法

使用

Des-3-(Furan-3-yl) 3-(Furan-2-yl) 10α-Hydroxy Nalfurafine is an impurity of Nalfurafine (N255600), a non-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid κ-agonist activity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test.

Des-3-(Furan-3-yl) 3-(Furan-2-yl) 10α-Hydroxy Nalfurafine 上流と下流の製品情報

原材料

準備製品


Des-3-(Furan-3-yl) 3-(Furan-2-yl) 10α-Hydroxy Nalfurafine 生産企業

Global( 7)Suppliers
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  • 2133305-36-7
  • 2-Propenamide, N-[(5α,6β,10α)-17-(cyclopropylmethyl)-4,5-epoxy-3,10,14-trihydroxymorphinan-6-yl]-3-(2-furanyl)-N-methyl-, (2E)-
  • (E)-N-((4R,4aS,7R,7aR,12bS,13S)-3-(Cyclopropylmethyl)-4a,9,13-trihydroxy-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl)-3-(furan-2-yl)-N-methylacrylamide
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