ソマトスタチンアセタート 化学特性,用途語,生産方法
説明
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. It is a somatostatin (SST) receptor agonist that binds to SST
1, SST
2, SST
3, SST
4, and SST
5 (IC
50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors). It inhibits cAMP accumulation induced by forskolin in CCL39 cells expressing human recombinant SST
1, SST
2, SST
3, SST
4, and SST
5 (EC
50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively). Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.
ソマトスタチンアセタート 上流と下流の製品情報
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