P-[[[(1R,2S)-2-AMINOCYCLOHEXYL]AMINO]CARBONYL]-PHOSPHONIC ACID 化学特性,用途語,生産方法
説明
Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins, thus enabling cell migration. Overexpression of MMPs are linked to diseases such as cancer, arthritis, osteoporosis, and arteriosclerosis.
cis-
ACCP is a reversible and competitive inhibitor of type IV collagen-
specific MMP-
2 and MMP-
9 with preference towards MMP-
2 (IC
50 = 4 and 20 μM, respectively). At 100 μM,
cis-
ACCP prevents 90% of tumor cell invasion across matrigel-
coated membranes
in vitro.
P-[[[(1R,2S)-2-AMINOCYCLOHEXYL]AMINO]CARBONYL]-PHOSPHONIC ACID 上流と下流の製品情報
原材料
準備製品