PMK ethyl glycidate

PMK ethyl glycidate 化学特性,用途語,生産方法

説明

PMK ethyl glycidate is an analytical reference standard categorized as a precursor in the synthesis of methylenedioxy phenethylamines and amphetamines, including 3,4-MDMA. This product is intended for research and forensic applications.

使用

NSC 195099 can be used as an analytical reference standard.

主な応用

PMK methyl glycidate is applied as immediate precursors of 3,4-methylenedioxymethamphetamine. 

合成

To a solution of piperonal (1, 3.00 g, 19.9 mmol) in CH2Cl2 (100 mL) was added (carbethoxyethylidene)triphenylphosphorane (2,14.5 g, 40.0 mmol), and the reaction mixture was stirred for 24 h at room temperature. The mixture was then concentrated at reduced pressure, and the residue was purified by flash column chromatography on silica gel (hexanes/EtOAc,10:1) to afford olefin 3 (4.45 g, 95%) as a colorless oil: 1H NMR (400 MHz, CDCl3) d 7.58 (s, 1H), 6.92 (d, J = 1.7 Hz, 1H), 6.90 (dd, J = 7.9, 1.7 Hz, 1H), 6.82 (d, J = 8.0 Hz, 1H), 5.97 (s, 2H), 4.24 (q, J = 7.1 Hz, 2H), 2.10 (d, J = 1.6 Hz, 3H),1.33 (t, J = 7.1 Hz, 3H); 13C NMR (100 MHz, CDCl3) d 168.7,147.6, 138.3, 129.9, 126.9, 124.6, 109.5, 108.2, 101.2,  60.7, 14.3,1 4.0; IR (ATR, cm-1): 2981, 2902,1698, 1628, 1502, 1489,1442, 1258, 1224; HRMS (EI) m/z calcd for C13H14O4 (M+) 234.0892, found 234.0895.
Fig The synthetic step of PMK ethyl glycidate

PMK ethyl glycidate 上流と下流の製品情報

原材料

準備製品

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• 28578-16-7
• 3,4-MDP-2P ethyl ester
• Pharmaceutical intermediates 2-Oxiranecarboxylicacid
• 2-Oxiranecarboxylicacid, 3-(1,3-benzod.../3,4-MDP-2-P intermediate
• new p 28578-16-7
• 3-(1,3-benzod.../3,4-MDP-2-P intermediate
• BMK CAS 28578-16-7
• Ethyl 3-(1,3-benzodioxol-5-yl)-2-methyl-2-oxiranecarboxylate
• Ethyl 3-(1,3-benzodioxol-5-yl)-2-methyloxirane-2-carboxylate Liquid
• PMK BMK
• new pmk oil
• OXIRANECARBOXYLICACID, 3-(1,3-BENZODIOXOL-5-YL)-2-METHYL-, ETHYL ESTER
• /PMK / BMK / PMK ethyl glycidate
• BMK PMK Oil
• Ethyl Glycidate Oil
• 99% Purity White crystilline powder ethyl 3-(1,3-benzodioxol-5-yl)-2-methyloxirane-2-carboxylate
• GLYCIDATE oil
• PMK ethyl glycidate (PMK powder&oil)
• pmk, 3-(1,3-benzodioxol-5-yl)-2-Methyl-
• NEW PMK,Pmk,Pmk Glycidate Oil
• PMK ethyl glycidate
• 3,4-MDP-2-P intermediate
• 2-Oxiranecarboxylicacid, 3-(1,3-benzodioxol-5-yl)-2-Methyl-, ethyl ester
• ethyl 3-(benzo[d][1,3]dioxol-5-yl)-2-methyloxirane-2-carboxylate
• 3-(1,3-benzodioxol-5-yl)-2-Methyl-
• cheap 3,4-MDP-2P ethyl ester
• Pmk Glycidate Oil
• GLYCIDATE
• ethyl 3-(1,3-benzodioxol-5-yl)-2-methyloxirane-2-carboxylate
• New PMK
• PMK liquid