Anti-MLL4 化学特性,用途語,生産方法
一般的な説明
This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. (provided by RefSeq)
Biochem/physiol Actions
PANK2 acts as a key regulatory enzyme in coenzyme A biosynthesis. Mutation in the gene is associated with the development of neurodegeneration with brain iron accumulation (NBIA).
Anti-MLL4 上流と下流の製品情報
原材料
準備製品