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SR-9243

化学構造式
1613028-81-1
CAS番号.
1613028-81-1
化学名:
别名:
英語名:
SR-9243
英語别名:
CS-1645;SR-9243;SR 9243;SR9243;SR-9243;N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-;N-(3-Bromophenethyl)-2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide;N-(3-bromophenethyl)-2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide;N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]benzenesulfonamide;Benzenesulfonamide, N-[2-(3-bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]-
CBNumber:
CB23035285
化学式:
C31H32BrNO4S2
分子量:
626.62
MOL File:
1613028-81-1.mol

SR-9243 物理性質

融点 :
154-155°C
沸点 :
786.3±70.0 °C(Predicted)
比重(密度) :
1.347±0.06 g/cm3(Predicted)
貯蔵温度 :
2-8°C
溶解性:
DMSOに可溶 (25 mg/ml以上)
酸解離定数(Pka):
-6.90±0.70(Predicted)
外見 :
個体
色:
白い
安定性：:
-20°C の DMSO 溶液で最大 3 か月間保存できます。

安全性情報

HSコード  29350090

SR-9243 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

SR-9243 化学特性,用途語,生産方法

説明

The liver X receptors (LXRs) are nuclear receptors that act as ligand-dependent transcription factors. They modulate lipid, cholesterol, and carbohydrate metabolism and homeostasis. SR9243 is a cell-permeable LXR inverse agonist that induces LXR-corepressor interaction at nanomolar concentrations. It reduces cancer cell viability (IC50 values range from 15 to 104 nM) without cytotoxicity against non-malignant cells. SR9243 disrupts the Warburg effect in cancer cells, suppressing the expression of glycolytic and lipogenic genes and reducing glycolytic metabolites and lipid production. It is effective in vivo, blocking glycolytic and lipogenic gene expression and inducing apoptosis in colon cancer xenografts without inducing weight loss in mice.

使用

SR9243 is used in new compounds targeting warburg effcts, killing cancer cells and inhibiting lipid production.

SR-9243 上流と下流の製品情報

原材料

準備製品

SR-9243 生産企業

Global( 101)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32760 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30253 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
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Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10522 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6393 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152
 Mandy@hangyubiotech.com China 10978 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43348 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57511 58

  スペクトルデータ(1HNMR)

SR-9243(1613028-81-1)1HNMR

1613028-81-1()キーワード:

SR8278 SRPIN340 N-(2-(3-(ピペラジン-1-イルメチル)イミダゾ[2,1-B]チアゾール-6-イル)フェニル)キノキサリン-2-カルボキサミド SR-27897 SR-12813 3-[[(4-クロロベンジル)(5-ニトロチオフェン-2-イルメチル)アミノ]メチル]ピロリジン-1-カルボン酸エチル N-ペンチル-3-[[(4-クロロベンジル)(5-ニトロチオフェン-2-イルメチル)アミノ]メチル]ピロリジン-1-カルボアミド
  • 1613028-81-1
  • SR-9243
  • N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]benzenesulfonamide
  • N-(3-bromophenethyl)-2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide
  • Benzenesulfonamide, N-[2-(3-bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]-
  • CS-1645
  • SR 9243;SR9243;SR-9243
  • N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-
  • N-(3-Bromophenethyl)-2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide
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