(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide 化学特性,用途語,生産方法
説明
HDAC8-IN-1 is an inhibitor of histone deacetylase 8 (HDAC8; IC
50 = 27.2 nM). It is selective for HDAC8 over HDAC1-3, -4, -6, -10, and -11 (IC
50s = ≥3,000 nM for all). HDAC8-IN-1 is cytotoxic to A549, H1299, and CL1-5 lung cancer cells (IC
50s = 7.9, 7.2, and 7 μM, respectively).
使用
(2E)-N-Hydroxy-3-(5-methoxy[1,1'':4'',1''''-terphenyl]-2-yl)-2-propenamide, is a HDAC8 inhibitor with an IC50 of 27.2 nM.
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide 上流と下流の製品情報
原材料
準備製品