プロパルギルブロミド 化学特性,用途語,生産方法
外観
無色～うすい黄色, 澄明の液体
溶解性
水に不溶, エタノール, アセトンに易溶。エタノール及びアセトンに極めて溶けやすく、水にほとんど溶けない。
用途
農薬全般(中間体を含む) 医薬,医薬中間体
使用上の注意
不活性ガス封入
説明
Propargyl bromide is a Shock sensitive liquid, lachrymator. Supplied
as an 80% solution in toluene stabilized with magnesium
oxide. Alternative formulations are currently under
development.
化学的特性
yellow solution
一般的な説明
A colorless to light yellow liquid substance with a sharp odor. Flash point 65°F. Denser than water and insoluble in water. Vapors are heavier than air. May be irritating to skin and eyes. Used to make other chemicals. 3-Bromopropyne may decompose explosively with mild shock.
空気と水の反応
Highly flammable. Insoluble in water.
反応プロフィール
3-Bromopropyne is soluble in alcohol, ether, chloroform, carbon tetrachloride and carbon disulfide. 3-Bromopropyne is highly flammable and a dangerous fire risk, sensitive to shock. 3-Bromopropyne is used in organic syntheses, preparation of resins and perfume intermediates [Hawley]. There is a high danger of formation of explosive metal acetylides, when 3-Bromopropyne comes in contact with copper, high-copper alloys, mercury, or silver.
危険性
Flammable, dangerous fire and explosion
risk. Irritant.
健康ハザード
3-Bromopropyne is very toxic via the oral route. If inhaled, may be harmful; contact may cause burns to skin and eyes.
火災危険
3-Bromopropyne detonates at 428F or more; ignites by impact. Emits highly toxic fumes of bromides when heated to decomposition. Reacts vigorously with oxidizing materials. Becomes shock-sensitive when mixed with chloropicrin. Unstable, avoid heat, flame, shock, and other chemicals
薬理学
Mode of action is considered
to be reaction with nucleophiles in living organisms.
安全性プロファイル
A poison by ingestion.
A dangerous fire hazard when exposed to
heat or flame. The aerated liquid may be
ignited by pressure. A dangerous, extremely
shock-sensitive explosive. It can detonate
when heated to 22O°C, by impact (especially
when mixed with chloropicrin), or when
heated whde confined. May explode on
contact with copper, high copper alloys,
mercury, or silver. Mixtures with
trichloronitromethane are shockand heat-
sensitive explosives. Can react vigorously
with oxidizing materials. To fight fire, use
water, foam, CO2, dry chemical. When
heated to decomposition it emits highly
toxic fumes of Br-. See also ACETYLENE
COMPOUNDS and BROMIDES.
代謝
Reacts slowly with water
to yield propargyl alcohol and bromide ion. It is expected
to move as a typical fumigant through the soil. Probably
not an ozone-depleting substance due to decomposition on
absorption of ultraviolet light.
プロパルギルブロミド 上流と下流の製品情報
原材料
準備製品