ピマバンセリン酒石酸塩
ピマバンセリン酒石酸塩 物理性質
- 貯蔵温度 :
- Store at -20°C
- 溶解性:
- DMSO:70.0(Max Conc. mg/mL);69.6(Max Conc. mM)
- 外見 :
- Solid
- 色:
- White to off-white
ピマバンセリン酒石酸塩 価格
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製品番号 |
製品説明 |
CAS番号 |
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ピマバンセリン酒石酸塩 化学特性,用途語,生産方法
効能
パーキンソン病治療薬, 統合失調症治療薬
説明
Pimavanserin,
developed by San Diego-based Acadia Pharmaceuticals, is a
selective and potent serotonin 2A (5-HT2A) receptor inverse
agonist. The USFDA approved this once-daily drug to treat
the delusions and hallucinations associated with psychosis as a
function of Parkinson’s disease. Pimavanserin has a unique mechanism of action relative to other antipsychotics, behaving
as a selective inverse agonist of the serotonin 5-HT2A receptor
while exhibiting 40-fold selectivity over the 5-HT2C receptor
and having no significant affinity or activity with the 5-HT2B or
dopamine receptors.
使用
Pimavanserin tartrate is a 5-HT2A inverse agonist that reverses psychosis-like behaviours and has the potential to treat various other neuropsychiatric disorders such as schizophrenia and Parkinson’s disease.
定義
ChEBI: A tartrate salt that is the hemitartrate salt of pimavanserin. An atypical antipsychotic that is used for treatment of hallucinations and delusions associated with Parkinson's disease.
ピマバンセリン酒石酸塩 上流と下流の製品情報
原材料
準備製品
ピマバンセリン酒石酸塩 生産企業
Global( 146)Suppliers
ピマバンセリン酒石酸塩 スペクトルデータ(1HNMR)
706782-28-7(ピマバンセリン酒石酸塩)キーワード:
- 706782-28-7
- N-(4-Fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1)
- N-(4-Fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl)carbamide
- Unii-na83F1sjsr
- Pimavanserin tartrate or ACP 103
- BVF-048
- Pimavanserin tartrate,nuplazid
- N-[(4-Fluorophenyl)methyl]-N-(1-methyl-4-piperidinyl)-N'-[[4-(2-methylpropoxy)phenyl]methyl]urea (2R,3R)-2,3-dihydroxybutanedioate (2:1)
- N-[(4-Fluorophenyl)methyl]-N-(1-methyl-4-piperidinyl)-N'-[[4-(2-methylpropoxy)phenyl]methyl]urea (2R,3R)-2,3-dihydroxybutanedioate
- Urea,N-[(4-fluorobenzyl)methyl]-N-(1-methyl-4-piperidinyl)-N'-[[4-(2-methylpropoxy)phenyl]methyl]-,(2R,3R)-2,3-dihydroxybutanediooate(2:1)
- ACP-103 tartrate
- 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea hemi((2R,3R)-2,3-dihydroxysuccinate)
- Pimavanserin tartrare
- 8-Octanedioic acid
- Pimavanserin Impurity reference
- Pimo van Serine L-tartrate
- Nuplazid
- ACP-103
- PiMavanserin Tartrate
- Pimavanserin tartaric acid
- Pimavanserin tartrate vv
- Pimavanserin L-Hetartrate
- ピマバンセリン酒石酸塩